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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY GNTR-FAMILY)
CommentsMb0044c, -, len: 244 aa. Equivalent to Rv0043c,len: 244 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 244 aa overlap). Probable transcriptional regulator, GntR family, similar to others e.g. NP_420584.1|NC_002696 transcriptional regulator GntR family from Caulobacter crescentus (221 aa); NP_294539.1|NC_001263 transcriptional regulator GntR family from Deinococcus radiodurans (267 aa); YIN1_STRAM|P32425 hypothetical transcriptional regulatory protein from Streptomyces ambofaciens (236 aa), FASTA scores: opt: 170, E(): 9.8e-05, (27.6% identity in 127 aa overlap); etc. Similar also to SC9B10_7 from Streptomyces coelicolor FASTA score: E():0.00038; and Rv0165c|MTCI28_5 from Mycobacterium tuberculosis (264 aa), FASTA score: (27.7% identity in 130 aa overlap).
Functional categoryRegulatory proteins
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS4735048084-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0044c|Mb0044c
MPKKYGVKEKDQVVAHILNLLLTGKLRSGDRVDRNEIAHGLGVSRVPIQEALVQLEHDGIVSTRYHRGAFIERFDVATILEHHELDGLLNGIASARAAANPTPRILGQLDAVMRSLRNSKESRAFAECVWEYRRTVNDEYAGPRLHATIRASQNLIPRVFWMTYQNSRDDVLPFYEEENAAIHRREPEAARAACIGRSELMAQTMLAELFRRRVLVPPEGACPGPFGAPIPGFARSYQPSSPVP
      
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