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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
Productsingle-strand binding protein ssb (helix-destabilizing protein)
CommentsMb0055, ssb, len: 164 aa. Equivalent to Rv0054,len: 164 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 164 aa overlap). Probable ssb,single-strand binding protein, equivalent to highly similar to others e.g. SSB_MYCLE|P46390 single-strand binding protein from Mycobacterium leprae (140 aa), FASTA scores: opt: 792, E(): 0, (92.6% identity in 135 aa overlap); and AAK30583.1|AF349434 single-stranded DNA-binding protein from Mycobacterium smegmatis (165 aa). Also highly similar to others e.g. T36594 probable single-strand binding protein from Streptomyces coelicolor (199 aa); etc. Also similar to Rv2478c|MTV008_34c CONSERVED HYPOTHETICAL PROTEIN from Mycobacterium tuberculosis (161 aa), FASTA score: E (): 1.1e-06. Note that the putative product of this CDS corresponds to spot 3_210 identified in culture supernatant by proteomics at the Max-Planck-Institut fuer Infektionsbiologie (see citations below). BELONGS TO THE SSB FAMILY.
Functional categoryInformation pathways
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS5857659070+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0055|ssb
MAGDTTITIVGNLTADPELRFTPSGAAVANFTVASTPRIYDRQTGEWKDGEALFLRCNIWREAAENVAESLTRGARVIVSGRLKQRSFETREGEKRTVIEVEVDEIGPSLRYATAKVNKASRSGGFGSGSRPAPAQTSSASGDDPWGSAPASGSFGGGDDEPPF
      
Bibliography
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