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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPOSSIBLE CELLULASE CELA1 (ENDOGLUCANASE) (ENDO-1,4-BETA-GLUCANASE) (FI-CMCASE) (CARBOXYMETHYL CELLULASE)
CommentsMb0063, celA1, len: 380 aa. Equivalent to Rv0062,len: 380 aa, from Mycobacterium tuberculosis strain H37Rv,(99.7% identity in 380 aa overlap). Possible celA1,cellulase (EC 3.2.1.4), similar to many e.g. AB65568.1|AL136058 putative secreted endoglucanase (cellulase) from Streptomyces coelicolor (332 aa); P07984|GUNA_CELFI ENDOGLUCANASE A PRECURSOR from Cellulomonas fimi (449 aa); GUN1_STRHA|P33682 endoglucanase 1 precursor (cellulase) from STREPTOMYCES HALSTEDII (321 aa), FASTA scores: opt: 702, E(): 1. 2e-27,(38.9% identity in 319 aa overlap); etc. SEEMS TO BELONG TO CELLULASE FAMILY B (FAMILY 6 OF GLYCOSYL HYDROLASES). Note that previously known as celA.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS6554266684+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0063|celA1
MTRRTGQRWRGTLPGRRPWTRPAPATCRRHLAFVELRHYFARVMSSAIGSVARWIVPLLGVAAVASIGVIADPVRVVRAPALILVDAANPLAGKPFYVDPASAAMIAARNANPPNAELTSVANTPQSYWLDQAFPPATVGGTVARYTGAAQAAGAMPVLTLYGIPHRDCGSYASGGFATGTDYRGWIDAVASGLGSSPATIIVEPDALAMADCLSPDQRQERFDLVRYAVDTLTRDPAAAVYVDAGHSRWLSAEAMAARLNDVGVGRARGFSLNVSNFYTTDEEIGYGEAISGLTNGSHYVIDTSRNGAGPAPDAPLNWCNPSGRALGAPPTTATAGAHADAYLWIKRPGESDGTCGRGEPQAGRFVSQYAIDLAHNAGQ
      
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