Gene Mb0065 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameMb0065
Gene length2940 bp
IdentifierMb0065
Location 68610 bp
Protein summary information
Molecular mass107429.0 Da
Isoelectric point6.9746
Protein length979 amino acids
Orthologs
M. tuberculosis H37RvRv0064
M. tuberculosis MTBC0mtbc0_000070
Cross-references
UniProtQ7U2X8
UniProtKB/TrEMBLX2BDX2, Q7U2X8
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE CONSERVED TRANSMEMBRANE PROTEIN
CommentsMb0065, -, len: 979 aa. Equivalent to Rv0064, len: 979 aa, from Mycobacterium tuberculosis strain H37Rv,(99.5% identity in 979 aa overlap). Probable conserved transmembrane protein, highly similar to NP_301532.1| (NC_002677) putative integral membrane protein from Mycobacterium leprae (983 aa). Also similar to other hypothetical proteins from ARCHAEOGLOBUS FULGIDUS and Synecocystis sp. e.g. P72637|D90899 HYPOTHETICAL 117.2 KD PROTEIN from SYNECHOCYSTIS SP. (1032 aa), FASTA scores: opt: 1004, E(): 3.6e-32, (31.0 % identity in 848 aa overlap); and CAC01334.1|AL390968 putative integral membrane protein (fragment) from Streptomyces coelicolor (815 aa); etc. Also similar to Rv3193c from Mycobacterium tuberculosis (992 aa), FASTA score: (50.3% identity in 985 aa overlap). Contains probable coiled-coil domain from aa 948 to 976.
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS6861071549+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0065|Mb0065
METGSPGKRPVLPKRARLLVTAGMGMLALLLFGPRLVDIYVDWLWFGEVGFRSVWITVLLTRLAIVAAVALVVAGIVLAALLLAYRSRPFFVPDEPQRDPVAPLRSAVMRRPRLFGWGIAVTLGVVCGLIASFDWVKVQLFVHGGTFGIVDPEFGYDIGFFVFDLPFYRSVLNWLFVAVVLAFLASLLTHYLFGGLRLTTGRGMLTQAARVQLAVFAGAVVLLKAVAYWLDRYELLSSGRKEPTFTGAGYTDIHAELPAKLVLVAIAVLCAVSFFTAIFLRDLRIPAMAAALLVLSAILVGGLWPLLMEQFSVRPNAADVERPYIQRNIEATREAYRIGGDWVQYRSYPGIGTKQPRDVPVDVTTIAKVRLLDPHILSRTFTQQQQLKNFFSFAEILDIDRYRIDGELQDYIVGVRELSPKSLTGNQTDWINKHIVYTHGNGFVAAPANRVNAAARDAENISDSNSGYPIYAVSDIASLGSGRQVIPVEQPRVYYGEVIAQADPDYAIVGGAPGSAPREYDTDTSKYTYTGAGGVSIGNWFNRTVFATKFAQHKFLFSREIGSESKVLIHRDPKERVQRVAPWLTTDDNPYPVVVNGRIVWIVDAYTTLDTYPYAQRSSLEGPVTSPTGIVRQGKQVSYVRNSVKATVDAYDGTVTLFQFDRDDPVLRTWMRAFPGTVKSEDQIPDELRAHFRYPEDLFEVQRSLLAKYHVDEPREFFTTNAFWSVPSDPTNDANATQPPFYVLVGDQQSAQPSFRLASAMVGYNREFLSAYISAHSDPANYGKLTVLELPTDTLTQGPQQIQNSMISDTRVASERTLLERSNRIHYGNLLSLPIADGGVLYVEPLYTERISTSPSSSTFPQLSRVLVSVREPRTEGGVRVGYAPTLAESLDQVFGPGTGRVATAPGGDAASAPPPGAGGPAPPQAVPPPRTTQPPAAPPRGPDVPPATVAELRETLADLRAVLDRLEKAIDAAETPGG
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