Gene Mb0075
in Mycobacterium bovis AF2122/97
General annotation
Type | CDS |
Function | Unknown |
Product | PROBABLE GLUTAMINE-TRANSPORT PROTEIN ABC TRANSPORTER GLNQ |
Comments | Mb0075, -, len: 70 aa. Equivalent to 3' end of Rv0073, len: 330 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 70 aa overlap). Probable glutamine-transport ATP-binding protein ABC-transporter (see citation below), similar to many ATP-binding proteins e.g. NP_070646.1|NC_000917 ABC transporter ATP-binding protein from Archaeoglobus fulgidus (231 aa); T34822 ABC-transporter ATP binding protein from Streptomyces coelicolor (230 aa); YBJZ_ECOLI|P75831 hypothetical ABC transporter ATP-binding protein from Escherichia coli (648 aa), FASTA scores: opt: 531, E(): 6.8e-30, (38.6% identity in 233 aa overlap); etc. Also highly similar to Y0A4_MYCT|Q50734|MTCY9C4.04c hypothetical ABC transporter ATP-binding protein from Mycobacterium tuberculosis (330 aa), FASTA scores: E(): 0, (83.3% identity in 330 aa overlap). Contains PS00017 ATP/GTP-binding site motif A (P-loop), PS00211 ABC transporters family signature, and PS00889 Cyclic nucleotide-binding domain signature 2. BELONGS TO THE ATP-BINDING TRANSPORT PROTEIN FAMILY (ABC TRANSPORTERS). Note that supposed act with near ORF Rv0072|MTV030.16 transmembrane ABC-transporter. REMARK-M.bovis-M.tuberculosis: In Mycobacterium tuberculosis strain H37Rv, Rv0073 exists as a single gene. In Mycobacterium bovis, a frameshift due to a single base deletion (a-*) splits Rv0073 into 2 parts, Mb0074 and Mb0075. |
Functional category | |
Mutant | Check for mutants available at TARGET website |
Coordinates
Type | Start | End | Orientation |
---|---|---|---|
CDS | 82491 | 82703 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Bibliography
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