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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN
CommentsMb0080, -, len: 201 aa. Equivalent to Rv0078, len: 201 aa, from Mycobacterium tuberculosis strain H37Rv,(99.5% identity in 201 aa overlap). Probable transcriptional regulator, equivalent to NP_302706.1|NC_002677 putative TetR-family transcriptional regulator from Mycobacterium leprae (236 aa), FASTA scores: opt: 755, E(): 0, (71.4% identity in 175 aa overlap). Also similar to others e.g. NP_103770.1|NC_002678 probable transcriptional regulator from Mesorhizobium loti (208 aa); NP_384275.1|NC_003047 PUTATIVE TRANSCRIPTION REGULATOR PROTEIN from Sinorhizobium meliloti (197 aa); NP_250960.1|NC_002516 probable transcriptional regulator from Pseudomonas aeruginosa (196 aa); etc. Also similar to TETC_ECOLI|P28815 transposon tn10 tetc protein from Escherichia coli (197 aa), FASTA scores: opt: 181, E(): 9.7e-05, (24.8% identity in 165 aa overlap). Contains probable helix-turn-helix motif from aa 35 to 56 (Score 1348, +3.78 SD).
Functional categoryRegulatory proteins
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS8656387168+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0080|Mb0080
MEIKRRTQEERSAATREALITGARKLWGLRGYAEVGTPEIATEAGVTRGAMYHQFADKAALFRDVVEVVEQDVMARMATLVAASGAATPADAIRAAVDAWLEVSGDPEVRQLVLLDAPVVLGWAGFRDVAQRYSLGMTEQLITEAIRAGQLARQPVRPLAQVLIGALDEAAMFIATADDPKRARRETRQVLRRLIDGMLNG
      
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