Gene Mb0087
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | POSSIBLE FORMATE HYDROGENLYASE HYCD (FHL) |
| Comments | Mb0087, hycD, len: 316 aa. Equivalent to Rv0084,len: 316 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 316 aa overlap). Possible hycD (alternate gene name: hevD), formate hydrogenlyase (EC 1.-.-.-), integral membrane protein, similar to others e.g. HYCD_ECOLI|P16430 formate hydrogenlyase subunit 4 from Escherichia coli (307 aa), FASTA scores: opt: 570,E(): 2.1e-26, (33.8% identity in 305 aa overlap); AAK06856.1|AF335723_2|AF335723 formate hydrogenlyase subunit 4 from Burkholderia pseudomallei (316 aa); NP_457244.1|NC_003198 formate hydrogenlyase subunit 4 from Salmonella enterica subsp. enterica serovar Typhi (307 aa); etc. Also similar to NUOH_ECOLI|P33603 NADH dehydrogenase I chain H from Escherichia coli (325 aa),FASTA scores: opt: 207, E(): 9.5e-06, (26.5% identity in 260 aa overlap). BELONGS TO THE COMPLEX I SUBUNIT 1 FAMILY. |
| Functional category | Intermediary metabolism and respiration |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 92363 | 93313 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0087|hycD
MSYLAGAAQIGGVMVGAPLVIGMTRQVRARWEGRAGAGLLQPWRDLLKQLGKQQITPAGTTIVFAAAPVIVAGTTLLIAAIAPLVATGSPLDPSADLFAVVGLLFLGTVALTLAGIDTGTSFGGMGASREITIAALVEPTILLAVFALSIPAGSANLGALVASTIDHPGHVVSLAGVLAFVALVIVIVAETGRLPVDNPATHLELTMVHEAMVLEYAGPRLALVEWAAGMRLTVLLALLANLFLPWGIAGAAPTALDVLTGVVAVAAKVAILAVLLATFEVFLAKLRLFRVPELLAGSFLLALLAVTAANFFTVGA
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