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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPOSSIBLE HYDROGENASE HYCQ
CommentsMb0089, hycQ, len: 488 aa. Equivalent to Rv0086,len: 488 aa, from Mycobacterium tuberculosis strain H37Rv,(99.8% identity in 488 aa overlap). Possible hycQ,hydrogenase (EC 1.-.-.-), integral membrane protein,weakly similar to P77437|HYFF_ECOLI HYDROGENASE-4 COMPONENT F from Escherichia coli (526 aa), FASTA scores: opt: 948, E(): 0, (35.9% identity in 493 aa overlap); and AAK06855.1|AF335723_1|AF335723 hydrogenase-4 component B from Burkholderia pseudomallei (668 aa). Also similar to d9087711 & NUOL_ECOLI|P33607 NADH dehydrogenase I chain L from Escherichia coli (613 aa), FASTA scores: opt: 360,E():3.2e-13, (27.9% identity in 488 aa overlap); and to NUON_ECOLI|P33608 NADH dehydrogenase I chain N from Escherichia coli (425 aa), FASTA scores: opt: 375, E(): 3.9e-14, (25.0% identity in 432 aa overlap).
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS9398695452+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0089|hycQ
MTGLLLAAILAPLAASIASLITGWRRTTATLTALSATTVLACAVAMGFWMGSGAQFGLGGLLRADALTVVMLVVIGIVGTLATAASIGYIDTELAHGHIDGRSARLYGVLTPAFLCATVLAVCANNIGVIWVAIEATTVITAFLVGHRRTRTALEATWKYVVICSVGIAVAFLGTVLLYFAARDSGAAAAGALNLDILAEHAAGLDPGVARLAGGLLLIGYGAKAGLFPFHTWLADAHSQAPAPVSALMSGVLLAVAFSVLIRLRPILDAVSGPAYLRNGLLVVGLATLLVAVLMLTVTGDVKRMLAYSSMEHMGLIAIAAAAGTTLAIAALLLHVLAHGIGKTVLFLAGGQLQAAHDSTAIADITGVMRRSRLIGVSFAVGLIVLLGLPPFAMFASELAIARSLANERLAWVLGAALLLIAIGFTALARNSGRMLLGTPAAGAPAITVPATAAAALMVGIVVSAALGITAGPLADLLGIAASNVGLP
      
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