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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
Productppe family protein ppe1
CommentsMb0099, PPE1, len: 463 aa. Equivalent to Rv0096,len: 463 aa, from Mycobacterium tuberculosis strain H37Rv,(99.8% identity in 463 aa overlap). Member of the Mycobacterium tuberculosis PPE family, similar to many e.g. Z46257|MLACEA_3 aceA gene for isocitrate L from M. leprae (438 aa), FASTA scores: opt: 1207, E(): 0, (55.3% identity in 380 aa overlap). Also similar to Z97559|MTCY261_19 from Mycobacterium tuberculosis (473 aa), FASTA score: (40.2% identity in 478 aa overlap); YHS6_MYCTU|P42611 hypothetical 50.6 kd protein (517 aa),FASTA scores: opt: 365, E(): 4.6e-12, (37.6% identity in 178 aa overlap). Also similar to MTCY274.23c from M. tuberculosis FASTA score: (31.1% identity in 383 overlap). Some similarity also to MTCY31.06c and MTCY48.17 and other mycobacterial PPE family proteins.
Functional categoryPe/ppe
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS105360106751+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0099|PPE1
MAIPPEVHSGLLSAGCGPGSLLVAAQQWQELSDQYALACAELGQLLGEVQASSWQGTAATQYVAAHGPYLAWLEQTAINSAVTAAQHVAAAAAYCSALAAMPTPAELAANHAIHGVLIATNFFGINTVPIALNEADYVRMWLQAADTMAAYQAVADAATVAVPSTQPAPPIRAPGGDAADTWLDVLSSIGQLIRDILDFIANPYKYFLEFFEQFGFSPAVTVVLALVALQLYDFLWYPYYASYGLLLLPFFTPTLSALTALSALIHLLNLPPAGLLPIAAALGPGDQWGANLAVAVTPATAAVPGGSPPTSNPAPAAPSSNSVGSASAAPGISYAVPGLAPPGVSSGPKAGTKSPDTAADTLATAGAARPGLARAHRRKRSESGVGIRGYRDEFLDATATVDAATDVPAPANAAGSQGAGTLGFAGTAPTTSGAAAGMVQLSSHSTSTTVPLLPTTWTTDAEQ
      
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