Gene Mb0123 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namefadD7
Gene length1578 bp
IdentifierMb0123
Location 144089 bp
Protein summary information
Molecular mass55158.8 Da
Isoelectric point6.4543
Protein length525 amino acids
Orthologs
M. tuberculosis H37RvRv0119
M. tuberculosis MTBC0mtbc0_000130
Cross-references
UniProtA0A1R3XUE7
InterProIPR000873, IPR020845, IPR025110
UniProtKB/TrEMBLQ7U2T6
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE FATTY-ACID-COA LIGASE FADD7 (FATTY-ACID-COA SYNTHETASE) (FATTY-ACID-COA SYNTHASE)
CommentsMb0123, fadD7, len: 525 aa. Equivalent to Rv0119,len: 525 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 525 aa overlap). Probable fadD7,fatty-acid-CoA synthetase (EC 6.2.1.-), similar to 4-coumarate:CoA ligase of many organisms e.g. U39405|PTU39405_1 4-coumarate:CoA ligase from Pinus taedaxylem (537 aa), FASTA scores: opt: 483, E(): 8.3e-22,(28.2% identity in 440 aa overlap). Contains PS00455 Putative AMP-binding domain signature. TBscore is 0.896.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS144089145666+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0123|fadD7
MASDFGPRIADLVEVAATRLPEAPALVVTADRIAISHRDLARLVDELAGQLTRSGLLPGDRVALRMGSNAEFVVALLAASRADLVVVPLDPALPITEQRVRSQAAGARVVLIDADGPHDRAEPTTRWWPLTVNVGGDSGPSGGTLSVHLDAATEPNPATSTPEGLRPDDAMIMFTGGTTGLPKMVPWTHANIASSVRAIITGYRLSPRDATVAVMPLYHGHGLIASLLATLASGGAVSLPARGRFSAHTFWDDIKAVGATWYTAVPTIHQILLERSATEPSGRKPAALRFIRSCSAPLTAQAALALQTEFAAPVVCAFGMTEATHQVTTTQIEGIDQTETPVVSTGLVGRSTGAQIRIVGSDGLPLPAGAVGEIWLRGTTVVRGYLGDPTITAANFTDGWLRTGDLGSLSAAGDLSIRGRIKELINRGGEKISPERVEGVLASHPNVMEAAVFGVPHQLYGEAVAAVIVPRESAPPTREELVQFCRERLAAFEIPASFQEASGLPHTAKGSLDRRAVAERFGHSV
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