Gene Mb0136c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namefadE1
Gene length1344 bp
IdentifierMb0136c
Location 158506 bp
Protein summary information
Molecular mass50223.6 Da
Isoelectric point7.8523
Protein length447 amino acids
Orthologs
M. tuberculosis H37RvRv0131c
M. tuberculosis MTBC0mtbc0_000142
Cross-references
UniProtA0A1R3XUG6
InterProIPR006091, IPR009075, IPR009100, IPR013786
UniProtKB/TrEMBLQ7U2S4
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE ACYL-CoA DEHYDROGENASE FADE1
CommentsMb0136c, fadE1, len: 447 aa. Equivalent to Rv0131c,len: 447 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 447 aa overlap). Probable fadE1,acyl-CoA dehydrogenase (EC 1.3.99.-), similar to many e.g. ACDS_HUMAN|P16219 acyl-CoA dehydrogenase short-chain specific precursor (412 aa), FASTA scores: opt: 522, E(): 1.4e-23, (30.1% identity in 425 aa overlap). Also highly similar to MTCI5_28 from Mycobacterium tuberculosis.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS158506159849-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0136c|fadE1
MPVRRRAGERLPTVWDFETDPQYQSKLDWVEKFMAEELEPLDLVALDPYDKKNADTMAILRPLQRQVKDQGLWAAHLRPELGGQGFGQVKLALLNEIIGRSRWAPSAFGCQAPDSGNAEILALFGTDEQKARYLRPLLDGEITSCYSMTEPQGGSDPGLFVTAATRDAAGNGDWIINGEKWFSTNAKHASFFIVMAVTKPEARTYEKMSLFIVPADTPGIEIVRNVGVGAESTRHASHGYIRYHDVRVPADHVLGGEGQAFMIAQTRLGGGRIHHAMRTIALARRAFDMMCERALSRQTRHGRLADLQMTQEKIADSWIQIEQFRLLVLRTAWLIDKHHDYQKVRRDIAAVKVAMPQVLHDVVQRAMHLHGALGVSDEMPFVKMMLAAESLGIADGATELHKMTVARRTLREYQPVTTLFPSQHIPTRRAHAEAWLAQRLEHAIAEF
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