Gene Mb0137c in Mycobacterium bovis AF2122/97
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information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namefgd2
Gene length1083 bp
IdentifierMb0137c
Location 159891 bp
Protein summary information
Molecular mass38444.4 Da
Isoelectric point6.7998
Protein length360 amino acids
Orthologs
M. tuberculosis H37RvRv0132c
M. tuberculosis MTBC0mtbc0_000143
Cross-references
UniProtA0A1R3XWK9
InterProIPR011251, IPR019945
UniProtKB/TrEMBLQ7U2S3
General annotation
TypeCDS
FunctionUnknown
Productputative f420-dependent glucose-6-phosphate dehydrogenase fgd2
CommentsMb0137c, fgd2, len: 360 aa. Equivalent to Rv0132c,len: 360 aa, from Mycobacterium tuberculosis strain H37Rv,(99.7% identity in 360 aa overlap). Putative fgd2,F420-dependent glucose-6-phosphate dehydrogenase (EC 1.-.-.-), highly similar to many from Mycobacteria e.g. AAD38167|g5031431 from Mycobacterium chelonae. Also similar to MJ1534|Q58929 N5,N10-METHYLENE TETRAHYDROMETHANOPTERIN REDUCTASE from METHANOCOCCUS JANNASCHII (342 aa), FASTA scores: opt: 285, E(): 7.9e-11,(28.4% identity in 292 aa overlap). And also similar to Rv0953c, Rv0791c, etc from Mycobacterium tuberculosis. Contains PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
Functional category-
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS159891160973-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0137c|fgd2
MTGISRRTFGLAAGFGAIGAGGLGGGCSTRSGPTPTPEPASRGVGVVLSHEQFRTDRLVAHAQAAEQAGFRYVWASDHLQPWQDNEGHSMFPWLTLALVGNSTSSILFGTGVTCPIYRYHPATVAQAFASLAILNPGRVFLGLGTGKRLNEQAATDTFGNYRERHDRLIEAIVLIRQLWSGERISFTGHYFRTDELKLYDTPAMPPPIFVAASGPQSATLAGRYGDGWIAQARDINDAKLLAAFAAGAQAAGRDPTTLGKRAELFAVVGDDKAAARAADLWRFTAGAVDQPNPVEIQRAAESNPIEKVLANWAVGTDPGVHIGAVQAVLDAGAVPFLHFPQDDPITAIDFYRTNVLPELR
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