Gene Mb0141 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namecyp138
Gene length1326 bp
IdentifierMb0141
Location 163556 bp
Protein summary information
Molecular mass49260.6 Da
Isoelectric point10.4764
Protein length441 amino acids
Orthologs
M. tuberculosis H37RvRv0136
M. tuberculosis MTBC0mtbc0_000147
Cross-references
UniProtP63718
UniProtKB/TrEMBLX2BE52, P63718
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE CYTOCHROME P450 138 CYP138
CommentsMb0141, cyp138, len: 441 aa. Equivalent to Rv0136,len: 441 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 441 aa overlap). Probable cyp138,cytochrome P450 138 (EC 1.14.-.-), similar to others e.g. SLR0574|Q59990 from SYNECHOCYSTIS SP. (444 aa), FASTA scores: opt: 315, E(): 1e-13, (25.7% identity in 416 aa overlap); etc. Also similar to MTV039_6 from Mycobacterium tuberculosis (472 aa), FASTA score: (38.2% identity in 442 aa overlap). Contains PS00017 ATP/GTP-binding site motif A (P-loop); and PS00086 Cytochrome P450 cysteine heme-iron ligand signature. BELONGS TO THE CYTOCHROME P450 FAMILY.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS163556164881+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0141|cyp138
MSEVVTAAPAPPVVRLPPAVRGPKLFQGLAFVVSRRRLLGRFVRRYGKAFTANILMYGRVVVVADPQLARQVFTSSPEELGNIQPNLSRMFGSGSVFALDGDDHRRRRRLLAPPFHGKSMKNYETIIEEETLRETANWPQGQAFATLPSMMHITLNAILRAIFGAGGSELDELRRLIPPWVTLGSRLAALPKPKRDYGRLSPWGRLAEWRRQYDTVIDKLIEAERADPNFADRTDVLALMLRSTYDDGSIMSRKDIGDELLTLLAAGHETTAATLGWAFERLSRHPDVLAALVEEVDNGGHELRQAAILEVQRARTVIDFAARRVNPPVYQLGEWVIPRGYSIIINIAQIHGDPDVFPQPDRFDPQRYIGSKPSPFAWIPFGGGTRRCVGAAFANMEMDVVLRTVLRHFTLETTTAAGERSHGRGVAFTPKDGGRVVMRRR
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