Gene Mb0148c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameMb0148c
Gene length1479 bp
IdentifierMb0148c
Location 168894 bp
Protein summary information
Molecular mass50774.1 Da
Isoelectric point8.1882
Protein length492 amino acids
Orthologs
M. tuberculosis H37RvRv0143c
M. tuberculosis MTBC0mtbc0_000154
Cross-references
UniProtA0A1R3XWM0
InterProIPR001807, IPR014743
UniProtKB/TrEMBLQ7U2R5
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE CONSERVED TRANSMEMBRANE PROTEIN
CommentsMb0148c, -, len: 492 aa. Equivalent to Rv0143c,len: 492 aa, from Mycobacterium tuberculosis strain H37Rv,(99.8% identity in 492 aa overlap). Probable conserved transmembrane protein, CIC family possibly involved in transport of chloride, similar to others and hypothetical proteins e.g. O28857 PUTATIVE CHLORIDE CHANNEL from Archaeoglobus fulgidus (589 aa), FASTA scores: opt: 966,E(): 0, (37.7% identity in 453 aa overlap); YADQ_ECOLI|P37019 hypothetical 46.0 kd protein (436 aa),FASTA scores: opt: 452, E(): 2.4e-20, (28.0% identity in 460 aa overlap).
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS168894170372-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0148c|Mb0148c
MAPGDWSVFAWHAANLPTMPEAEDIGNEAAGGRLGVSIRSAGYLRKWFLLGITIGVIAGLGAVVFYLALKYTSEFLLGYLADYQIPTPVGEGGHRGSTGFARPWAIPLVTTGGAVLSALIVAKLAPEATGHGTDEAIESVHGDPRAIRGRAVLVKMVASALTIGSGGSGGREGPTAQISAGFCSLLTRRLNLSNEDGRTAVALGIGAGIGAIFAAPLGGAALGASIPYRDDFDYRNLLPGFIASGTAYAVLGAFLGFDPLFGYIDAEYRFEKAWPLLWFVVIGLIAAAVGYLYARVFHASVAITRRLPGGPVLKPAIGGLLVGLLGLPIPQILSSGYGWAQLAADRGTLLSIPLWIVIVLPIAKILATSLSIGTGGSGGLFGPGIVIGAFVGAAIWRLGELTELPGVPHEPGIFVVVAMMACFGSVSRAPLAVMIMVAEMTGSFSVVPGAIIAVGIAALLLSRTNVTIYETQRLNRQTAEAERGGSDRPTTA
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