Gene Mb0149 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameMb0149
Gene length843 bp
IdentifierMb0149
Location 170474 bp
Protein summary information
Molecular mass30643.0 Da
Isoelectric point8.6794
Protein length280 amino acids
Orthologs
M. tuberculosis H37RvRv0144
M. tuberculosis MTBC0mtbc0_000155
Cross-references
UniProtA0A1R3XVL1
InterProIPR001647, IPR009057, IPR011075, IPR015893
UniProtKB/TrEMBLQ7U2R4
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (POSSIBLY TETR-FAMILY)
CommentsMb0149, -, len: 280 aa. Equivalent to Rv0144, len: 280 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 280 aa overlap). Probable transcriptional regulator, possibly tetR family. Has region similar to others e.g. Q59431|UIDR_ECOLI|GUSR|B1618|Z2623|ECS2326 UID OPERON REPRESSOR (GUS OPERON) from Escherichia coli strains K12 and O157:H7 (196 aa), FASTA scores: opt: 214, E(): 1.1e-06, (26.0% identity in 196 aa overlap). Contains probable helix-turn helix motif from aa 109-130 (Score 1463, +4.17 SD). COULD BELONG TO THE TETR/ACRR FAMILY OF TRANSCRIPTIONAL REGULATORS.
Functional categoryRegulatory proteins
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS170474171316+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0149|Mb0149
MPHSWTPTSVMTPPLVVAAFRPVGHYRLATDRAGGPCSPPATGAKLTSSVASRPTVGTKPQWWHTLVMSMSLTAGRGPGRPPAAKADETRKRILHAARQVFSERGYDGATFQEIAVRADLTRPAINHYFANKRVLYQEVVEQTHELVIVAGIERARREPTLMGRLAVVVDFAMEADAQYPASTAFLATTVLESQRHPELSRTENDAVRATREFLVWAVNDAIERGELAADVDVSSLAETLLVVLCGVGFYIGFVGSYQRMATITDSFQQLLAGTLWRPPT
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