Gene Mb0153 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameMb0153
Gene length861 bp
IdentifierMb0153
Location 175023 bp
Protein summary information
Molecular mass29778.7 Da
Isoelectric point5.1208
Protein length286 amino acids
Orthologs
M. tuberculosis H37RvRv0148
M. tuberculosis MTBC0mtbc0_000159
Cross-references
UniProtA0A1R3XUF8
InterProIPR002198, IPR002347, IPR016040, IPR020904
UniProtKB/TrEMBLQ7U2R0
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE
CommentsMb0153, -, len: 286 aa. Equivalent to Rv0148, len: 286 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 286 aa overlap). Probable short-chain dehydrogenase (EC 1.-.-.-), similar to others, in particular Estradiol 17 beta-dehydrogenases (EC 1.1.1.62),e.g. DHB4_MOUSE|P51660 estradiol 17 beta-dehydrogenase 4 (735 aa), FASTA scores: opt: 952, E(): 0, (52.5% identity in 276 aa overlap). Contains PS00061 Short-chain alcohol dehydrogenase family signature. BELONGS TO THE SHORT-CHAIN DEHYDROGENASES/REDUCTASES (SDR) FAMILY.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS175023175883+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0153|Mb0153
MPGVQDRVIVVTGAGGGLGREYALTLAGEGASVVVNDLGGARDGTGAGSAMADEVVAEIRDKGGRAVANYDSVATEDGAANIIKTALDEFGAVHGVVSNAGILRDGTFHKMSFENWDAVLKVHLYGGYHVLRAAWPHFREQSYGRVVVATSTSGLFGNFGQTNYGAAKLGLVGLINTLALEGAKYNIHANALAPIAATRMTQDILPPEVLEKLTPEFVAPVVAYLCTEECADNASVYVVGGGKVQRVALFGNDGANFDKPPSVQDVAARWAEITDLSGAKIAGFKL
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