Gene Mb0165c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namePE4
Gene length1509 bp
IdentifierMb0165c
Location 189121 bp
Protein summary information
Molecular mass53115.2 Da
Isoelectric point4.2727
Protein length502 amino acids
Orthologs
M. tuberculosis H37RvRv0160c
M. tuberculosis MTBC0mtbc0_000173
Cross-references
UniProtA0A1R3XUK0
InterProIPR000084, IPR013228
UniProtKB/TrEMBLQ7U2P8
General annotation
TypeCDS
FunctionUnknown
Productpe family protein pe4
CommentsMb0165c, PE4, len: 502 aa. Equivalent to Rv0160c,len: 502 aa, from Mycobacterium tuberculosis strain H37Rv,(99.6% identity in 502 aa overlap). Member of the Mycobacterium tuberculosis PE family, similar to many other PE proteins e.g. Z92770|MTCI5_26c from M. tuberculosis (525 aa), FASTA scores: opt: 816, E(): 0,(41.4% identity in 367 aa overlap); C-terminal region of O06801|RV1768|MTCY28.34 from Mycobacterium tuberculosis (618 aa), FASTA scores: opt: 417, E(): 6.7e-18, (53.5% identity in 142 aa overlap). Also highly similar to downstream ORF MTV032_2.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS189121190629-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0165c|PE4
MSHLVTAPDMLATAAAHVDEIASTLRAANAAAAGPTCNLLAAAGDEVSAATAALFSAYGREYQAVVKQAAAFHSEFTRTLEAAGNAYAHAEAANAARVSHALDTINAPIRTLLGRTPLSPNGSSGAGGLPAIAQLAAESPITALIMGGTNNPLPDPEYVTDINKAFIQTLFPGAVSQGLFTPEQFWPVTPDLGNLTFNQSVTEGVALLNTTVNNQLALDNKVVAFGYSQSATIINNYINSLMAMGSPNPDDISFVMIGSGNNPVGGLLARFPGFYIPFLDVPFNGATPANSPYPTHIYTAQYDGIAHAPQFPLRILSDINAFMGYFYVHNTYPELMATQVDNAVPLPTSPGYTGNTQYYMFLTQDLPLLQPIRDIPYAGPPIADLFQPQLRVLVDLGYADYGPGGNYADIPTPAGLFSIPNPFAVTYYLIKGSLQAPYGAIVEIGVEAGLIGPEWFPDSYPWVPSINPGLNFYFGQPQVTLLSLMSGGLGNILHLIPPPVFT
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