Gene Mb0203 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameMb0203
Gene length2247 bp
IdentifierMb0203
Location 232425 bp
Protein summary information
Molecular mass80965.7 Da
Isoelectric point6.1834
Protein length748 amino acids
Orthologs
M. tuberculosis H37RvRv0197
M. tuberculosis MTBC0mtbc0_000211
Cross-references
UniProtA0A1R3XUL4
InterProIPR006656, IPR006657, IPR006963, IPR009010
UniProtKB/TrEMBLQ7U2L3
General annotation
TypeCDS
FunctionUnknown
ProductPOSSIBLE OXIDOREDUCTASE
CommentsMb0203, -, len: 748 aa. Equivalent to Rv0197, len: 762 aa, from Mycobacterium tuberculosis strain H37Rv,(99.9% identity in 748 aa overlap). Possible oxidoreductase (EC 1.-.-.-), similar to others e.g. 9948789|AAG06102.1|AE004699_7|B83307 probable molybdopterin oxidoreductase from Pseudomonas aeruginosa strain PAO1 (769 aa); 5441785|CAB46809.1|AL096811|T36812 probable dehydrogenase from Streptomyces coelicolor (747 aa), FASTA scores: opt: 617, E(): 9.8e-30, (29.9% identity in 762 aa overlap); BAB04334.1|AP001509 assimilatory nitrate reductase (catalytic subunit) from Bacillus halodurans (743 aa); etc. REMARK-M.bovis-M.tuberculosis: In Mycobacterium bovis, a single base transversion (t-g) introduces a stop codon that leads to a shorter product compared to its homolog in Mycobacterium tuberculosis strain H37Rv (748 aa versus 762 aa).
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS232425234671+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0203|Mb0203
MTSSDWLPTACILCECNCGIVVQVDDRRLARIRGDKAHPGSAGYTCNKALRLDHYQNNRARLSSPMRRRADGTYEEIDWDTAIVEIAEGFKQIRDTHGGDKIFYYGGGGQGNHLGGAYSGAFLKALGSRYRSNALAQEKTGEAWVDFQLYGGHTRGEFENAEVSVFVGKNPWMSQSFPRARVVLNEIAKDPGRSMIVIDPVVTDTAKMADFHLRVQPGCDAWCLAALAAVLVQENLCNEAFLAAHVHGVDTVRAALQEVPVADYAQRCGVDEELLRAAARRIGTAASVSVFEDLGIQQAPNSTVCSYLNKLLWILTGNFAKKGGQHLHSSFAPLFSQVSGRTPVTGAPIIAGLIPGNVVPEEILTEHPDRFRAMIVESGNPAHSLADSAACRAAFQALELMVVVDVAMTETARLAHYVLPAASQFEKPEATFFNFEFPRNGFQLRRPLFPPLPGTLPEPEIWARLVRALGVVDEADLRPLREAAAQGRQAYTEAFLAAAATNPTVAKLTAYVLYETLGPTLPDGLAGAAALWGLAQKTAMAYPDAVRRAGHADGNALFDAILERPSGVTFTVHNYEDDFALISHPDHKIALEIPEMLAEIRSLTQTPSRLTTPQLPIVLSVGERRAYTANDIFRDPSWRKRDANGALRVSVEDAQALGLADGCLARITTAAGSAEATVEVTETMLAGHAALPNGFGLDYTGDDGRTVVAGVAPNALTSTRWRDPYAGTPWHKHVPAAIRRADAESPIW
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