Gene Mb0218c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namenadR
Gene length972 bp
IdentifierMb0218c
Location 253865 bp
Protein summary information
Molecular mass36031.3 Da
Isoelectric point6.9387
Protein length323 amino acids
Orthologs
M. tuberculosis H37RvRv0212c
M. tuberculosis MTBC0mtbc0_000226
Cross-references
UniProtA0A1R3XVT3
InterProIPR004821, IPR006417, IPR014729, IPR016429, IPR027417
UniProtKB/TrEMBLQ7U2K1
General annotation
TypeCDS
FunctionUnknown
ProductPOSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN NADR (PROBABLY ASNC-FAMILY)
CommentsMb0218c, nadR, len: 323 aa. Equivalent to Rv0212c,len: 323 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 323 aa overlap). Possible nadR (alternate gene name: nadI), transcriptional regulator,similar to others e.g. NADR_ECOLI|P27278 transcriptional regulator from Escherichia coli (410 aa), FASTA scores: opt: 377, E (): 1e-17, (31.1% identity in 347 aa overlap). Contains PS00017 ATP/GTP-binding site motif A (P-loop).
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS253865254836-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0218c|nadR
MTHGMVLGKFMPPHAGHVYLCEFARRWVDELTIVVGSTAAEPIPGAQRVAWMRELFPFDRVVHLANENPQRPWEHPDFWDIWKASLQGVLATRPDFVFGAEPYNADFAQVLGARFVAVDHGRTVVPVTATDIRADPLGHWQHIPRCVRPAFVKRVSIIGPESTGKTTLAQAVAEKLRTKWVPERAKMLRELNGGSLIGLEWAEIVRGQIASEEALARDADRVLICDTDPLATTVWAEFLAGGCPQELRDLARRPYDLTLLTTPDVPWDADDGRCVPGARGTFFARCEQALRAAGRSFVVITGGWEERLSVSLRAVEELVRARR
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