Gene Mb0236 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namefadE4
Gene length1707 bp
IdentifierMb0236
Location 274382 bp
Protein summary information
Molecular mass63494.8 Da
Isoelectric point6.0388
Protein length568 amino acids
Orthologs
M. tuberculosis H37RvRv0231
M. tuberculosis MTBC0mtbc0_000246
Cross-references
UniProtA0A1R3XUQ6
InterProIPR006091, IPR009075, IPR009100
UniProtKB/TrEMBLQ7U2I3
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE ACYL-COA DEHYDROGENASE FADE4
CommentsMb0236, fadE4, len: 568 aa. Equivalent to Rv0231,len: 568 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 568 aa overlap). Probable fadE4,acyl-CoA dehydrogenase (EC 1.3.99.-), similar to many e.g. O29752 ACYL-COA DEHYDROGENASE (ACD-3) from Archaeoglobus fulgidus (576 aa), FASTA scores: opt: 1788, E(): 0, (51.0% identity in 577 aa overlap); ACDB_BACSU|P45857 acyl-coa dehydrogenase from Bacillus subtilis (379 aa), FASTA scores: opt: 232, E(): 2.2e- 08, (21.6% identity in 291 aa overlap).
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS274382276088+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0236|fadE4
MLLNPNHLTRKYPDRRSGEIMAATVDFFESRGKARLKHDDHERIWYSDFLDFVGRERIFASLLTPASYGADDCRWDTYRISEFAEIMGFYGLSYWYPFQVTALGLGPIWMSANEDAKRKAAAGLEAGEVFAFGLSEQTHGADVYQTDMILTPSDGGWTANGEKYYIGNANVARMVSTFGKIAGTPESQEYVFFVADSQHERYDLIKNVVNSQNYVANYALRDYPVTEADILHRGAEAFHAALNTVNVCKYNLGWGAIGMCTHALYESVTHAANRHLYGTVVTDFSHVRRLLTDAYVRLIAMKLVASRASDYMRSASAADRRYLLYSPLTKAKVTSEGERVITALWDVIAAKGVEKDTFFETVAREIGLLPRLEGTVHINIGLLGKFMPNYLFAPDSTLPVIPRRDDAADDAFLFAQGPTGGLGKVRFHDWRASFDTCAHLPNVALLREQVDVFAELLASATPDAAQQKDIDFAFGVGQLFANVPYAQLILEEARLSGVDEALIDEIFGVLVRDFNTHAVELHGRSATTAEQARFAMRMVRRPVHDPARYDQIWKDHVLALNGAYQMAP
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