Gene Mb0238 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namenrdB
Gene length945 bp
IdentifierMb0238
Location 276909 bp
Protein summary information
Molecular mass35634.0 Da
Isoelectric point4.5195
Protein length314 amino acids
Orthologs
M. tuberculosis H37RvRv0233
M. tuberculosis MTBC0mtbc0_000248
Cross-references
UniProtQ7U2I1
UniProtKB/TrEMBLX2BEH1, Q7U2I1
General annotation
TypeCDS
FunctionUnknown
Productribonucleoside-diphosphate reductase (beta chain) nrdb (ribonucleotide reductase small chain)
CommentsMb0238, nrdB, len: 314 aa. Equivalent to Rv0233,len: 314 aa, from Mycobacterium tuberculosis strain H37Rv,(99.7% identity in 314 aa overlap). Probable nrdB (alternate gene name: rnrS) ribonucleoside-diphosphate reductase, beta chain (EC 1.17.4.1), similar to others e.g. RIR2_SCHPO|P36603 ribonucleoside-diphosphate reductase (391 aa), FASTA scores: opt: 168, E(): 0.00018,(26.1% identity in 199 aa overlap); etc. BELONGS TO THE RIBONUCLEOSIDE DIPHOSPHATE REDUCTASE SMALL CHAIN FAMILY. COFACTOR: BINDS 2 IRON IONS.
Functional categoryInformation pathways
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS276909277853+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0238|nrdB
MTRTRSGSLAAGGLNWASLPLKLFAGGNAKFWDPADIDFTRDRADWEKLSDDERDYATRLCTQFIAGEEAVTEDIQPFMSAMRAEGRLADEMYLTQFAFEEAKHTQVFRMWLDAVGISEDLHRYLDDLPAYRQIFYAELPECLNALSADPSPAAQVRASVTYNHIVEGMLALTGYYAWHKICVERAILPGMQELVRRIGDDERRHMAWGTFTCRRHVAADDANWTVFETRMNELIPLALRLIEEGFALYGDQPPFDLSKDDFLQYSTDKGMRRFGTISNARGRPVAEIDVDYSPAQLEDTFADEDRRTLAAASA
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