Gene Mb0359 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namegrpE
Gene length708 bp
IdentifierMb0359
Location 422738 bp
Protein summary information
Molecular mass24558.7 Da
Isoelectric point4.1657
Protein length235 amino acids
Orthologues
M. tuberculosisRv0351
Cross-references
UniProtQ7U272
UniProtKB/TrEMBLX2BET3, Q7U272
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE GRPE PROTEIN (HSP-70 COFACTOR)
CommentsMb0359, grpE, len: 235 aa. Equivalent to Rv0351,len: 235 aa, from Mycobacterium tuberculosis strain H37Rv,(99.6% identity in 235 aa overlap). Probable grpE protein (HSP-70 COFACTOR), equivalent to CAC32012.1|AL583925 Hsp70 cofactor from Mycobacterium leprae (229 aa). Also highly similar to others eg Q05562|GRPE_STRCO|2127521|PN0643 GRPE PROTEIN from Streptomyces coelicolor (225 aa). Contains grpE protein signature (PS01071). BELONGS TO THE GRPE FAMILY.
Functional categoryVirulence, detoxification, adaptation
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS422738423445+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0359|grpE
MTDGNQKPDGNSGEQVTVTDKRRIDPETGEVRHVPPGDMPGGTAAADAAHTEDKVAELTADLQRVQADFANYRKRALRDQQAAADRAKASVVSQLLGVLDDLERARKHGDLESGPLKSVADKLDSALTGLGLVAFGAEGEDFDPVLHEAVQHEGDGGQGSKPVIGTVMRQGYQLGEQVLRHALVGVVDTVVVDAAELESVDDGTAVADTAENDQADQGNSADTLGEQAESEPSGS
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