Gene Mb0370c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namefba
Gene length1035 bp
IdentifierMb0370c
Location 442282 bp
Protein summary information
Molecular mass36544.5 Da
Isoelectric point5.5853
Protein length344 amino acids
Cross-references
UniProtP67476
UniProtKB/TrEMBLX2BEQ4, P67476
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE FRUCTOSE-BISPHOSPHATE ALDOLASE FBA
CommentsMb0370c, fba, len: 344 aa. Equivalent to Rv0363c,len: 344 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 344 aa overlap). Probable fba (alternate gene name: fda), fructose bisphosphate aldolase (EC 4.1.2.13), equivalent to AL023514|MLCB4_18|O69600|ALF_MYCLE FRUCTOSE-BISPHOSPHATE ALDOLASE from Mycobacterium leprae (345 aa), FASTA scores: opt: 1995, E(): 0, (87.7% identity in 342 aa overlap). Also highly similar to others. BELONGS TO CLASS II FRUCTOSE-BISPHOSPHATE ALDOLASE FAMILY. COFACTOR: ZINC.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS442282443316-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0370c|fba
MPIATPEVYAEMLGQAKQNSYAFPAINCTSSETVNAAIKGFADAGSDGIIQFSTGGAEFGSGLGVKDMVTGAVALAEFTHVIAAKYPVNVALHTDHCPKDKLDSYVRPLLAISAQRVSKGGNPLFQSHMWDGSAVPIDENLAIAQELLKAAAAAKIILEIEIGVVGGEEDGVANEINEKLYTSPEDFEKTIEALGAGEHGKYLLAATFGNVHGVYKPGNVKLRPDILAQGQQVAAAKLGLPADAKPFDFVFHGGSGSLKSEIEEALRYGVVKMNVDTDTQYAFTRPIAGHMFTNYDGVLKVDGEVGVKKVYDPRSYLKKAEASMSQRVVQACNDLHCAGKSLTH
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