Gene Mb0378c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameMb0378c
Gene length594 bp
IdentifierMb0378c
Location 449057 bp
Protein summary information
Molecular mass21116.3 Da
Isoelectric point7.5617
Protein length197 amino acids
Orthologs
M. tuberculosis MTBC0mtbc0_000391
M. tuberculosis H37RvRv0371c
Cross-references
UniProtA0A1R3XV43
InterProIPR025877
UniProtKB/TrEMBLQ7U256
General annotation
TypeCDS
FunctionUnknown
ProductCONSERVED HYPOTHETICAL PROTEIN
CommentsMb0378c, -, len: 197 aa. Equivalent to Rv0371c,len: 197 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 197 aa overlap). Conserved hypothetical protein, similar to other hypothetical proteins e.g. AL132824|SCAH10.09c|CAB60163.1|AL132824 hypothetical protein from Streptomyces coelicolor (207 aa), FASTA scores: opt: 247, E(): 4.5e-09, (32.3% identity in 195 aa overlap). Also weak similarity with YURE|D70017|Z99120|BSUB0017_134 hypothetical protein yurE from Bacillus subtilis (197 aa), FASTA scores: opt: 217,E(): 2.5e-08, (27.0% identity in 174 aa overlap).
Functional categoryConserved hypotheticals
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS449057449650-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0378c|Mb0378c
MTATQITGVVLAAGRSNRLGTPKQLLPYRDTTVLGATLDVARQAGFDQLILTLGGAASAVRAAMALDGTDVVVVEDVERGCAASLRVALARVHPRATGIVLMLGDQPQVAPATLRRIIDVGPATEIMVCRYADGVGHPFWFSRTVFGELARLHGDKGVWKLVHSGRHPVRELAVDGCVPLDVDTWDDYRRLLESVPS
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