Gene Mb0395 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namepurT
Gene length1260 bp
IdentifierMb0395
Location 469354 bp
Protein summary information
Molecular mass43593.6 Da
Isoelectric point4.5726
Protein length419 amino acids
Orthologs
M. tuberculosis H37RvRv0389
M. tuberculosis MTBC0mtbc0_000408
Cross-references
UniProtA0A1R3XV63
InterProIPR003135, IPR005862, IPR011761, IPR013815, IPR013816, IPR016185
UniProtKB/TrEMBLQ7U241
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE 2 PURT (GART 2) (GAR TRANSFORMYLASE 2) (5'-PHOSPHORIBOSYLGLYCINAMIDE TRANSFORMYLASE 2) (FORMATE-DEPENDENT GAR TRANSFORMYLASE)
CommentsMb0395, purT, len: 419 aa. Equivalent to Rv0389,len: 419 aa, from Mycobacterium tuberculosis strain H37Rv,(99.5% identity in 419 aa overlap). Probable purT,phosphoribosylglycinamide formyltransferase 2 (EC 2.1.2.-), similar to others e.g. P33221|PURT_ECOLI|B1849 phosphoribosylglycinamide formyltransferase 2 from Escherichia coli strain K-12 (391 aa), FASTA scores: opt: 481, E(): 1.3e-22, (40.1% identity in 379 aa overlap); etc. BELONGS TO THE PURK / PURT FAMILY. COFACTOR: MAGNESIUM.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS469354470613+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0395|purT
MIDGWTEGQHEPTVRHERPAAPQDVRRVMLLGSAEPSRELAIALQGLGAEVIAVDGYVGAPAHRIADQSVVVTMTDAEELTAVIRRLQPDFLVTVTAAVSVDALDAVEQADGECTELVPNARAVRCTADREGLRRLAADQLGLPTAPFWFVGSLGELQAVAVHAGFPLLVSPVAGVAGQGSSVVAGPNEVEPAWQRAAGHQVQPQTGGVSPRVCAESVVEIEFLVTMIVVCSQGPNGPLIEFCAPIGHRDADAGELESWQPQKLSTAALDAAKSIAARIVKALGGRGVFGVELMINGDEVYFADVTVCPAGSAWVTVRSQRLSVFELQARATLGLAVDTLMISPGAARVINPDHTAGRAAVGAAPPADALTGALGVPESDVVIFGRGLGVALATAPEVAIARERAREVASRLNVPDSRE
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