Gene Mb0414c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameMb0414c
Gene length819 bp
IdentifierMb0414c
Location 490906 bp
Protein summary information
Molecular mass29220.4 Da
Isoelectric point8.3263
Protein length272 amino acids
Orthologs
M. tuberculosis H37RvRv0406c
M. tuberculosis MTBC0mtbc0_000426
Cross-references
UniProtA0A1R3XV84
InterProIPR001279
UniProtKB/TrEMBLQ7U223
General annotation
TypeCDS
FunctionUnknown
ProductBETA LACTAMASE LIKE PROTEIN
CommentsMb0414c, -, len: 272 aa. Equivalent to Rv0406c,len: 272 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 272 aa overlap). Beta-lactamase-like protein, equivalent to AAD38170.1|AF152397_1 beta-lactamase-like protein from Mycobacterium phlei (243 aa); AL023514|MLCB4_8 hypothetical protein from Mycobacterium leprae (251 aa), FASTA scores: opt: 1284,E(): 0, (74.9% identity in 243 aa overlap); and AAD38164.1|AF152394_2 beta-lactamase-like protein from Mycobacterium avium (247 aa), FASTA scores: opt: 1301,E(): 0, (74.2% identity in 244 aa overlap); etc. Also slight similarity to others beta-lactamases and hypothetical proteins e.g. P52700|BLA1_XANMA|628530|S45349 METALLO-BETA-LACTAMASE L1 PRECURSOR (BETA-LACTAMASE, TYPE II) (PENICILLINASE) from Xanthomonas maltophilia (290 aa),FASTA scores: (34.4% identity in 96 aa overlap).
Functional categoryConserved hypotheticals
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS490906491724-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0414c|Mb0414c
MVATRGTRLAALALAPRLAGMAELVQITDKVHLARGHAVNWVLVTDDTGVLLIDAGYPGDRAEVLASLNKLGYTPGDVRAIVLTHAHIDHLGSAIWFAREHSTPVYCHAEEVGHAKREYRENASVFDVALRSWRPRVAVWGIHLLRRGGLTGDGIPTAQPLTAEAAAGLPGQPMAIFTPGHTSGHCSYVVDGVLASGDALITGHPMLRHRGPQLLPAVFSHSQQNSIRSLAALALLETNILAPGHGELWHGPIRKATDEALERAQKSNHVFR
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