Gene Mb0421 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namemutT3
Gene length654 bp
IdentifierMb0421
Location 500732 bp
Protein summary information
Molecular mass23499.2 Da
Isoelectric point4.809
Protein length217 amino acids
Orthologs
M. tuberculosis H37RvRv0413
M. tuberculosis MTBC0mtbc0_000433
Cross-references
UniProtA0A1R3XVU3
InterProIPR000086, IPR015797, IPR020084, IPR020476
UniProtKB/TrEMBLQ7U218
General annotation
TypeCDS
FunctionUnknown
ProductPOSSIBLE MUTATOR PROTEIN MUTT3 (7,8-DIHYDRO-8-OXOGUANINE-TRIPHOSPHATASE) (8-OXO-DGTPASE) (DGTP PYROPHOSPHOHYDROLASE)
CommentsMb0421, mutT3, len: 217 aa. Equivalent to Rv0413,len: 217 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 217 aa overlap). Possible mutT3,mutator protein (EC 3.6.1.-), showing some similarity with e.g. MUTT_PROVU|P32090 mutator mutt protein from Proteus vulgaris (112 aa), FASTA scores: opt: 151, E(): 0.0008,(40.7% identity in 59 aa overlap). SEEMS TO BELONG TO THE NUDIX HYDROLASE FAMILY.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS500732501385+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0421|mutT3
MPSCPPAYSEQVRGDGDGWVVSDSGVAYWGRYGAAGLLLRAPRPDGTPAVLLQHRALWSHQGGTWGLPGGARDSHETPEQTAVRESSEEAGLSAERLEVRATVVTAEVCGVDDTHWTYTTVVADAGELLDTVPNRESAELRWVAENEVADLPLHPGFAASWQRLRTAPATVPLARCDERRQRLPRTIQIEAGVFLWCTPGDADQAPSPLGRRISSLL
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