Gene Mb0435c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namexthA
Gene length876 bp
IdentifierMb0435c
Location 517036 bp
Protein summary information
Molecular mass32108.3 Da
Isoelectric point5.0145
Protein length291 amino acids
Orthologs
M. tuberculosis H37RvRv0427c
M. tuberculosis MTBC0mtbc0_000449
Cross-references
UniProtA0A1R3XVA3
InterProIPR004808, IPR005135
UniProtKB/TrEMBLQ7U208
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE EXODEOXYRIBONUCLEASE III PROTEIN XTHA (EXONUCLEASE III) (EXO III) (AP ENDONUCLEASE VI)
CommentsMb0435c, xthA, len: 291 aa. Equivalent to Rv0427c,len: 291 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 291 aa overlap). Probable xthA (alternate gene name: xth), exodeoxyribonuclease III protein (EC 3.1.11.2), similar to others e.g. EX3_ECOLI|P09030 exodeoxyribonuclease III from Escherichia Coli strain K12 (268 aa), FASTA scores: opt: 360, E(): 1.2e-17, (29.3% identity in 270 aa overlap); etc. BELONGS TO THE AP/EXOA FAMILY OF DNA REPAIR ENZYMES.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS517036517911-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0435c|xthA
MPDGTIDGGHPQRPASPRLRSPLLRLATWNVNSIRTRLDRVLDWLGRADVDVLAMQETKCPDGQFPALPLFELGYDVAHVGFDQWNGVAIASRVGLDDVRVGFDGQPSWSGKPEVAATTEARALGATCGGIRVWSLYVPNGRALDDPHYTYKLDWLAALRDTAEGWLRDDPAAPIALMGDWNIAPTDDDVWSTEFFAGCTHVSEPERKAFNAIVDAQFTDVVRPFTPGPGVYTYWDYTQLRFPKKQGMRIDFILGSPALAARVMDAQIVREERKGKAPSDHAPVLVDLHAG
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