Gene Mb0437c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namedef
Gene length594 bp
IdentifierMb0437c
Location 518822 bp
Protein summary information
Molecular mass20968.8 Da
Isoelectric point4.6908
Protein length197 amino acids
Orthologs
M. tuberculosis H37RvRv0429c
M. tuberculosis MTBC0mtbc0_000451
Cross-references
UniProtQ7U206
UniProtKB/TrEMBLX2BF02, Q7U206
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE POLYPEPTIDE DEFORMYLASE DEF (PDF) (FORMYLMETHIONINE DEFORMYLASE)
CommentsMb0437c, def, len: 197 aa. Equivalent to Rv0429c,len: 197 aa, from Mycobacterium tuberculosis strain H37Rv,(99.5% identity in 197 aa overlap). Probable def,polypeptide deformylase (EC 3.5.1.31), equivalent to CAC30884.1|AL583923 polypeptide deformylase from Mycobacterium leprae (197 aa). Also similar to others e.g. DEF_ECOLI|P27251|95874|S23107 polypeptide deformylase from Escherichia coli (169 aa), FASTA scores: opt: 179, E(): 1.8e-05, (34.6% identity in 162 aa overlap); etc. BELONGS TO THE POLYPEPTIDE DEFORMYLASE FAMILY. COFACTOR: BINDS 1 ZINC ION.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS518822519415-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0437c|def
MTVVPIRIVGDPVLHTATTPVTVAADGSLPADLAQLIATMYDTMDAANGVGLAANQIGCSLRLFVYDCAADRAMTARRRGVVINPVLETSEIPETMPDPDTDDEGCLSVPGESFPTGRAKWARVTGLDADGSPVSIEGTGLFARMLQHETGHLDGFLYLDRLIGRYARNAKRAVKSHGWGVPGLSWLPGEDPDPFGH
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