Gene Mb0444c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namepssA
Gene length861 bp
IdentifierMb0444c
Location 525549 bp
Protein summary information
Molecular mass31260.3 Da
Isoelectric point10.7942
Protein length286 amino acids
Orthologs
M. tuberculosis H37RvRv0436c
M. tuberculosis MTBC0mtbc0_000458
Cross-references
UniProtP59949
UniProtKB/TrEMBLX2BEX8, P59949
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE CDP-DIACYLGLYCEROL--SERINE O-PHOSPHATIDYLTRANSFERASE PSSA (PS SYNTHASE) (PHOSPHATIDYLSERINE SYNTHASE)
CommentsMb0444c, pssA, len: 286 aa. Equivalent to Rv0436c,len: 286 aa, from Mycobacterium tuberculosis strain H37Rv,(99.7% identity in 286 aa overlap). Probable pssA, PS synthase (CDP-diacylglycerol--serine O-phosphatidyltransferase) (EC 2.7.8.8) (see citation below), integral membrane protein, equivalent to AL035159|MLCB1450_9|T44730 from Mycobacterium leprae (300 aa), FASTA scores: opt: 1506, E(): 0, (77.9% identity in 285 aa overlap). Also highly similar to others e.g. NP_108059.1|14027250|BAB54204.1|AP003012 phosphatidylserine synthase from Mesorhizobium loti (248 aa); PSS_BACSU|P39823 cdp-diacylglycerol--serine o-phosphatidyltransferase from Bacillus subtilis (177 aa),FASTA scores: opt: 277, E(): 9.9e-12, (33.3% identity in 183 aa overlap); etc. Contains PS00379 CDP-alcohol phosphatidyltransferases signature. BELONGS TO THE CDP-ALCOHOL PHOSPHATIDYLTRANSFERASE CLASS-I FAMILY.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS525549526409-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0444c|pssA
MIGKPRGRRGVNLQILPSAMTVLSICAGLTAIKFALEHQPKAAMALIAAAAILDGLDGRVARILDAQSRMGAEIDSLADAVNFGVTPALVLYVSMLSKWPVGWVVVLLYAVCVVLRLARYNALQDDGTQPAYAHEFFVGMPAPAGAVSMIGLLALKMQFGEGWWTSVWFLSFWVTGTSILLVSGIPMKKMHAVSVPPNYAAALLAVLAICAAAAVLAPYLLIWVIIIAYMCHIPFAVRSQRWLAQHPEVWDDKPKQRRAVRRASRRAHPYRPSMARLGLRKPGRRL
Bibliography
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