Gene Mb0454c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameMb0454c
Gene length771 bp
IdentifierMb0454c
Location 535464 bp
Protein summary information
Molecular mass28253.1 Da
Isoelectric point11.0266
Protein length256 amino acids
Orthologs
M. tuberculosis H37RvRv0446c
M. tuberculosis MTBC0mtbc0_000468
Cross-references
UniProtA0A1R3XVC7
InterProIPR001104, IPR010721
UniProtKB/TrEMBLQ7U1Z5
General annotation
TypeCDS
FunctionUnknown
ProductPOSSIBLE CONSERVED TRANSMEMBRANE PROTEIN
CommentsMb0454c, -, len: 256 aa. Equivalent to Rv0446c,len: 256 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 256 aa overlap). Possible conserved transmembrane protein, similar at N-terminus to U1740AF|U15183|MLU15183_40 from Mycobacterium leprae (117 aa), FASTA scores: opt: 175, E(): 2.5e-05, (62.5% identity in 40 aa overlap); and at C-terminus to AL021529|SC10A5_3 from Streptomyces coelicolor (226 aa), FASTA scores: opt: 207, E(): 9.8e-07, (34.2% identity in 114 aa overlap). Also similar to others hypothetical proteins e.g. AAK04680.1|AE006291_14|AE006291) HYPOTHETICAL PROTEIN from Lactococcus lactis subsp. lactis (257 aa).
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS535464536234-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0454c|Mb0454c
MVTSVSALAVAVVHSVAFAIGRRIGRYNVVDVVWGLGFVAVAVAAATLGHGDPVRRWLLLALVSTWGLRLSWHMYRKTAGQGEDPRYADLLRGATPVQALRKVFGLQGLLTLFVSFPLQLSAVTGPTPKPLLAVGGVGLAVWLVGITFEAVGDWQLWVFKSDPANRGVIMDRGLWAWTRHPNYFGDACVWWGLWLITINDWAPLATVGSPLLMTYLLVDVSGARLTERYLKGRPGFAEYQRRTAYFVPRPPRSARR
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