Gene Mb0459c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namemmpS4
Gene length423 bp
IdentifierMb0459c
Location 542507 bp
Protein summary information
Molecular mass15403.5 Da
Isoelectric point6.7798
Protein length140 amino acids
Orthologs
M. tuberculosis H37RvRv0451c
M. tuberculosis MTBC0mtbc0_000473
Cross-references
UniProtP0A5K3
UniProtKB/TrEMBLX2BEZ3, P0A5K3
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE CONSERVED MEMBRANE PROTEIN MMPS4
CommentsMb0459c, mmpS4, len: 140 aa. Equivalent to Rv0451c,len: 140 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 140 aa overlap). Probable mmpS4,conserved membrane protein (see citations below),equivalent to U1740W|P54880|YV33_MYCLE HYPOTHETICAL 16.9 kDa PROTEIN from Mycobacterium leprae (154 aa), FASTA scores: opt: 727, E(): 0, (75.9% identity in 137 aa overlap). Also similar to other Mycobacterial proteins e.g. Z84725|MTCY04D9.16c from Mycobacterium tuberculosis (142 aa), FASTA scores: opt: 451, E(): 3.2e-24, (50.0% identity in 138 aa overlap); etc. BELONGS TO THE MMPS FAMILY. TBparse score is 0.953.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS542507542929-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0459c|mmpS4
MLMRTWIPLVILVVVIVGGFTVHRIRGFFGSENRPSYSDTNLENSKPFNPKHLTYEIFGPPGTVADISYFDVNSEPQRVDGAVLPWSLHITTNDAAVMGNIVAQGNSDSIGCRITVDGKVRAERVSNEVNAYTYCLVKSA
Bibliography
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