Gene Mb0477 in Mycobacterium bovis AF2122/97
Go to browser
virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namefadB2
Gene length861 bp
IdentifierMb0477
Location 559914 bp
Protein summary information
Molecular mass30728.5 Da
Isoelectric point4.949
Protein length286 amino acids
Cross-references
UniProtA0A1R3XXL1
InterProIPR006108, IPR006176, IPR008927, IPR013328, IPR016040, IPR022694
UniProtKB/TrEMBLQ7U1X6
General annotation
TypeCDS
FunctionUnknown
Product3-hydroxybutyryl-coa dehydrogenase fadb2 (beta-hydroxybutyryl-coa dehydrogenase) (bhbd)
CommentsMb0477, fadB2, len: 286 aa. Equivalent to Rv0468,len: 286 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 286 aa overlap). Probable fadB2,3-hydroxybutyryl-CoA dehydrogenase (EC 1.1.1.157),equivalent to CAC31978.1|AL583925 3-hydroxyacyl-CoA dehydrogenase from Mycobacterium leprae (287 aa). Also similar to many 3-hydroxybutyryl-CoA dehydrogenases e.g. U32229|BJU32229_1 beta-hydroxybutyryl coenzyme A dehydrogenase from Bradyrhizobium japonicum (293 aa),FASTA scores: opt: 771, E(): 0, (45.7% identity in 282 aa overlap). BELONGS TO THE 3-HYDROXYACYL-COA DEHYDROGENASE FAMILY.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS559914560774+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0477|fadB2
MSDAIQRVGVVGAGQMGSGIAEVSARAGVEVTVFEPAEALITAGRNRIVKSLERAVSAGKVTERERDRALGLLTFTTDLNDLSDRQLVIEAVVEDEAVKSEIFAELDRVVTDPDAVLASNTSSIPIMKVAAATKQPQRVLGLHFFNPVPVLPLVELVRTLVTDEAAAARTEEFASTVLGKQVVRCSDRSGFVVNALLVPYLLSAIRMVEAGFATVEDVDKAVVAGLSHPMGPLRLSDLVGLDTLKLIADKMFEEFKEPHYGPPPLLLRMVEAGQLGKKSGRGFYTY
Bibliography
No article yet recorded