Gene Mb0494c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameMb0494c
Gene length756 bp
IdentifierMb0494c
Location 574009 bp
Protein summary information
Molecular mass26416.1 Da
Isoelectric point8.9984
Protein length251 amino acids
Orthologues
M. tuberculosisRv0484c
Cross-references
UniProtA0A1R3XVE6
InterProIPR002198, IPR002347, IPR016040
UniProtKB/TrEMBLQ7U1W7
General annotation
TypeCDS
FunctionUnknown
Productprobable short-chain type oxidoreductase
CommentsMb0494c, -, len: 251 aa. Equivalent to Rv0484c,len: 251 aa, from Mycobacterium tuberculosis strain H37Rv,(99.6% identity in 251 aa overlap). Probable short-chain oxidoreductase (EC 1.-.-.-), highly similar to others e.g. T36118|4678912|CAB41284.1|AL049707 probable oxidoreductase from Streptomyces coelicolor (260 aa); YDFG_HAEIN|P45200|HI1430 hypothetical oxidoreductase (SDR family) from Haemophilus influenzae (252 aa), FASTA scores: opt: 496, E(): 7.9e-25, (35.0 % identity in 243 aa overlap); etc. BELONGS TO THE SHORT-CHAIN DEHYDROGENASES/REDUCTASES (SDR) FAMILY. STRONG SIMILARITY,TO BACTERIAL YDFG HOMOLOGS.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS574009574764-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0494c|Mb0494c
MTTIGTRKRVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGTAIVADVTDDAAVEALARALSRVDVLVNNAGGAKGLQFVADADLEHWRWMWDTNVLGTLRVTRALLPKLIDSGDGLIVTVTSIAALEVYDGGAGYTAAKHAQGALHRTLRGELLGKPVRLTEIAPGAVETEFSLVRFDGDQQRADAVYAGMTPLVAADVAEVIGFVATRPSHVNLDQIVIRPRDQASASRRATHPVR
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