Gene Mb0499 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namegpm1
Gene length750 bp
IdentifierMb0499
Location 579447 bp
Protein summary information
Molecular mass27215.8 Da
Isoelectric point5.3443
Protein length249 amino acids
Orthologues
M. tuberculosisRv0489
Cross-references
UniProtP0A5R7
UniProtKB/TrEMBLX2BF75, P0A5R7
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE PHOSPHOGLYCERATE MUTASE 1 GPM1 (PHOSPHOGLYCEROMUTASE) (PGAM) (BPG-DEPENDENT PGAM)
CommentsMb0499, gpm1, len: 249 aa. Equivalent to Rv0489,len: 249 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 249 aa overlap). Probable gpm1,phosphoglycerate mutase 1 (EC 5.4.2.1), equivalent to P53531|PMGY_MYCLE PHOSPHOGLYCERATE MUTASE from Mycobacterium leprae (247 aa). Also highly similar to others e.g. PMG1_ECOLI|P31217 (249 aa), FASTA scores: opt: 805, E(): 0, (51.4% identity in 245 aa overlap); etc. Contains PS00175 Phosphoglycerate mutase family phosphohistidine signature, and PS00017 ATP/GTP-binding site motif A (P-loop). BELONGS TO THE PHOSPHOGLYCERATE MUTASE FAMILY. Note that previously known as gpm.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS579447580196+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0499|gpm1
MANTGSLVLLRHGESDWNALNLFTGWVDVGLTDKGQAEAVRSGELIAEHDLLPDVLYTSLLRRAITTAHLALDSADRLWIPVRRSWRLNERHYGALQGLDKAETKARYGEEQFMAWRRSYDTPPPPIERGSQFSQDADPRYADIGGGPLTECLADVVARFLPYFTDVIVGDLRVGKTVLIVAHGNSLRALVKHLDQMSDDEIVGLNIPTGIPLRYDLDSAMRPLVRGGTYLDPEAAAAGAAAVAGQGRG
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