Gene Mb0500
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | PUTATIVE TWO COMPONENT SENSOR HISTIDINE KINASE SENX3 |
| Comments | Mb0500, senX3, len: 410 aa. Equivalent to Rv0490,len: 410 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 410 aa overlap). Putative senX3,two-component sensor histidine kinase (EC 2.7.3.-),transmembrane protein (see citations below), equivalent to O07129|SEX3_MYCBO SENSOR-LIKE HISTIDINE KINASE SENX3 from Mycobacterium bovis BCG (410 aa), FASTA scores: E(): 0,(99.5% identity in 410 aa overlap); and highly similar to P54883|SEX3_MYCLE|SENX3 SENSOR-LIKE HISTIDINE KINASE from Mycobacterium leprae (443 aa), FASTA score: (83.8% identity in 408 aa overlap). Also highly similar, except in N-terminus, to CAC31957.1|AL583925 probable two-component system sensor histidine kinase from Mycobacterium leprae (441 aa). Also highly similar to sensor kinase proteins from other organisms e.g. CAB77323.1|AL160331 putative sensor kinase protein from Streptomyces coelicolor (426 aa). |
| Functional category | |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 580370 | 581602 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0500|senX3
MTVFSALLLAGVLSALALAVGGAVGMRLTSRVVEQRQRVATEWSGITVSQMLQCIVTLMPLGAAVVDTHRDVVYLNERAKELGLVRDRQLDDQAWRAARQALGGEDVEFDLSPRKRSATGRSGLSVHGHARLLSEEDRRFAVVFVHDQSDYARMEAARRDFVANVSHELKTPVGAMALLAEALLASADDSETVRRFAEKVLIEANRLGDMVAELIELSRLQGAERLPNMTDVDVDTIVSEAISRHKVAADNADIEVRTDAPSNLRVLGDQTLLVTALANLVSNAIAYSPRGSLVSISRRRRGANIEIAVTDRGIGIAPEDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAANHDGTIRVWSKPGTGSTFTLALPALIEAYHDDERPEQAREPELRSNRSQREEELSR
Bibliography
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