Gene Mb0502c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameMb0502c
Gene length1890 bp
IdentifierMb0502c
Location 582640 bp
Protein summary information
Molecular mass66188.2 Da
Isoelectric point9.626
Protein length629 amino acids
Orthologs
M. tuberculosis H37RvRv0492c
M. tuberculosis MTBC0mtbc0_000517
Cross-references
UniProtA0A1R3XVL2
InterProIPR000172, IPR007867
UniProtKB/TrEMBLQ7U1W6
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE OXIDOREDUCTASE GMC-TYPE
CommentsMb0502c, -, len: 629 aa. Equivalent to Rv0492c,len: 629 aa, from Mycobacterium tuberculosis strain H37Rv,(99.8% identity in 629 aa overlap). Probable oxidoreductase GMC type (EC 1.-.-.-), similar to others except in N-terminus e.g. P55582|AE000087_5|Y4NJ_RHISN HYPOTHETICAL GMC-TYPE OXIDOREDUCTASE from Rhizobium sp. (505 aa), FASTA scores: opt: 873, E():0, (34.3% identity in 502 aa overlap); YTH2_RHOER|P46371 HYPOTHETICAL 53.0 kd GMC-TYPE OXIDOREDUCTASE from Rhodococcus erythropolis (493 aa), FASTA score: (25.7% identity in 521 aa overlap); YTH2_RHOSO|P46371 hypothetical 53.0 kd gmc-type oxidoreductase from Rhodococcus erythropolis (493 aa),FASTA score: (25.7% identity in 521 aa overlap); NP_085596.1|NC_002679 probable oxidoreductase from Mesorhizobium loti (507 aa); NP_285451.1|NC_001264 GMC oxidoreductase from Deinococcus radiodurans (722 aa); NP_249055.1|NC_002516 probable oxidoreductase from Pseudomonas aeruginosa (531 aa); etc. Contains PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature,and PS00624 GMC oxidoreductases signature 2. BELONGS TO THE GMC OXIDOREDUCTASES FAMILY. COFACTOR: FAD (BY SIMILARITY). Note that start changed since first submission (previously 684 aa).
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS582640584529-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0502c|Mb0502c
MSRLADRAKSYPLASFGAALLPPELGGPLPAQFVQRVDRYVTRLPATSRFAVRAGLASLAAASYLTTGRSLPRLHPDERARVLHRIAALSPEVAAAVEGLKAIVLLANGADTYAHELLARAQEHDAARPDAELTVILSADSPSVTRADAVVVGSGAGGAMVARTLARAGLDVVVLEEGRRWTVEEFRSTHPVDRYAGLYRGAGATVALGRPAVVLPMGRAVGGTTVVNSGTCFRPSLAVQRRWRDEFGLGLADPDQLGRRLDDAEQTLRVAPVPLEIMGRNGRLLLQAAKSLGWRAAPIPRNAPGCRGCCQCAIGCPSNAKFGVHLNALPQACAAGARIISWARVERILHRAGRAYGVRARRPDGTTLDVLADAVVVAAGATETPGLLRRSGLGGHPRLGHNLALHPATMLAGLFDDDVFAWRGVLQSAAVHEFHESDGVLIEATSTPPGMGSMVFPGYGAELLRWLDRAPQIATFGAMVADRGVGTVRSVRGETVVRYDIAPGEIAKLRVALQAIGRLFFAAGAVEVLTGIPGAPPMRSLPELQDVLRRANPRSLHLAAFHPTGTAAAGADEQLCPVDATGRLRGVEGVWVADASILPSCPEVNPQLSIMAMALAVADQTVAKVVGVR
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