Gene Mb0511 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameproC
Gene length888 bp
IdentifierMb0511
Location 591234 bp
Protein summary information
Molecular mass30157.5 Da
Isoelectric point4.4119
Protein length295 amino acids
Orthologs
M. tuberculosis H37RvRv0500
M. tuberculosis MTBC0mtbc0_000526
Cross-references
UniProtA0A1R3XVG8
InterProIPR000304, IPR008927, IPR016040, IPR028939
UniProtKB/TrEMBLQ7U1W3
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE PYRROLINE-5-CARBOXYLATE REDUCTASE PROC (P5CR) (P5C REDUCTASE)
CommentsMb0511, proC, len: 295 aa. Equivalent to Rv0500,len: 295 aa, from Mycobacterium tuberculosis strain H37Rv,(99.7% identity in 295 aa overlap). Probable proC,Pyrroline-5-carboxylate reductase (EC 1.5.1.2) (see citation below), equivalent to P46725|PROC_MYCLE PYRROLINE-5-CARBOXYLATE REDUCTASE from Mycobacterium leprae (294 aa), FASTA scores: opt: 1473, E(): 0, (82.4% identity in 295 aa overlap). Also similar to others e.g. P46540|PROC_CORGL PYRROLINE-5-CARBOXYLATE REDUCTASE from Corynebacterium glutamicum (270 aa); T36286|4803683|CAB42663.1|AL049819 pyrroline-5-carboxylate reductase from Streptomyces coelicolor (284 aa); etc. BELONGS TO THE PYRROLINE-5-CARBOXYLATE REDUCTASE FAMILY.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS591234592121+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0511|proC
MLFGMARIAIIGGGSIGEALLSGLLRAGRQVKDLVVAERMPDRANYLAQTYSVLVTSAADAVENATFVVVAVKPADVEPVIADLANATAAAENDSAEQVFVTVVAGITIAYFESKLPAGTPVVRAMPNAAALVGAGVTALAKGRFVTPQQLEEVSALFDAVGGVLTVPESQLDAVTAVSGSGPAYFFLLVEALVDAGVGVGLSRQVATDLAAQTMAGSAAMLLERMDQDQGGANGELMGLRVDLTASRLRAAVTSPGGTTAAALRELERGGFRMAVDAAVQAAKSRSEQLRITPE
Bibliography
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