Gene Mb0547c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namefabH
Gene length1008 bp
IdentifierMb0547c
Location 625717 bp
Protein summary information
Molecular mass34872.5 Da
Isoelectric point4.7712
Protein length335 amino acids
Cross-references
UniProtP0A575
UniProtKB/TrEMBLX2BF69, P0A575
General annotation
TypeCDS
FunctionUnknown
Product3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE III FABH (BETA-KETOACYL-ACP SYNTHASE III) (KAS III)
CommentsMb0547c, fabH, len: 335 aa. Equivalent to Rv0533c,len: 335 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 335 aa overlap). fabH (alternate gene name: mtFabH), 3-oxoacyl-[acyl-carrier protein] synthase III (EC 2.3.1.41) (see citations below), highly similar to others e.g. Q54206|FABH from STREPTOMYCES GLAUCESCENS (333 aa), FASTA scores: opt: 1109, E(): 0, (51.4% identity in 333 aa overlap); FABH_ECOLI|P24249 3-oxoacyl-[acyl-carrier-protein] synthase III (317 aa),FASTA scores: opt: 666, E(): 0, (37.1% identity in 318 aa overlap); etc. BELONGS TO THE FABH FAMILY. Note that previously known as fabH.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS625717626724-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0547c|fabH
MTEIATTSGARSVGLLSVGAYRPERVVTNDEICQHIDSSDEWIYTRTGIKTRRFAADDESAASMATEACRRALSNAGLSAADIDGVIVTTNTHFLQTPPAAPMVAASLGAKGILGFDLSAGCAGFGYALGAAADMIRGGGAATMLVVGTEKLSPTIDMYDRGNCFIFADGAAAVVVGETPFQGIGPTVAGSDGEQADAIRQDIDWITFAQNPSGPRPFVRLEGPAVFRWAAFKMGDVGRRAMDAAGVRPDQIDVFVPHQANSRINELLVKNLQLRPDAVVANDIEHTGNTSAASIPLAMAELLTTGAAKPGDLALLIGYGAGLSYAAQVVRMPKG
Bibliography
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