Gene Mb0548c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namemenA
Gene length879 bp
IdentifierMb0548c
Location 626806 bp
Protein summary information
Molecular mass30014.3 Da
Isoelectric point10.1063
Protein length292 amino acids
Orthologs
M. tuberculosis H37RvRv0534c
M. tuberculosis MTBC0mtbc0_000563
Cross-references
UniProtP65651
UniProtKB/TrEMBLX2BFB9, P65651
General annotation
TypeCDS
FunctionUnknown
Product1,4-DIHYDROXY-2-NAPHTHOATE OCTAPRENYLTRANSFERASE MENA (DHNA-OCTAPRENYLTRANSFERASE)
CommentsMb0548c, menA, len: 292 aa. Equivalent to Rv0534c,len: 292 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 292 aa overlap). Probable menA,1,4-dihydroxy-2-naphthoate octaprenyltransferase (EC 2.5.1.-), integral membrane protein, equivalent to Y13803|MLB1306_2|NP_302556.1 probable 4-dihydroxy-2-naphthoate octaprenyltransferase from Mycobacterium leprae (294 aa), FASTA scores: opt: 1509,E(): 0, (80.2% identity in 288 aa overlap). Also highly similar to others e.g. MENA_ECOLI|P32166|B3930 from Escherichia coli (308 aa), FASTA scores: opt: 495, E(): 2.9e-25, (36.3 identity in 289 aa overlap); etc. BELONGS TO THE MENA FAMILY.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS626806627684-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0548c|menA
MASFAQWVSGARPRTLPNAIAPVVAGTGAAAWLHAAVWWKALLALAVAVALVIGVNYANDYSDGIRGTDDDRVGPVRLVGSRLATPRSVLTAAMTSLALGALAGLVLALLSAPWLIAVGAICIAGAWLYTGGSKPYGYAGFGELAVFVFFGPVAVLGTQYTQALRVDWVGLAQAVATGALSCSVLVANNLRDIPTDARADKITLAVRLGDARTRMLYQGLLAVAGVLTFVLMLATPWCVVGLVAAPLALRAAGPVRSGRGGRELIPVLRDTGLAMLVWALAVAGALAFGQLS
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