Gene Mb0562c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namemenB
Gene length945 bp
IdentifierMb0562c
Location 640256 bp
Protein summary information
Molecular mass34689.0 Da
Isoelectric point6.4241
Protein length314 amino acids
Orthologs
M. tuberculosis H37RvRv0548c
M. tuberculosis MTBC0mtbc0_000577
Cross-references
UniProtA0A1R3XVP6
InterProIPR001753, IPR010198, IPR014748
UniProtKB/TrEMBLQ7U1T0
General annotation
TypeCDS
FunctionUnknown
Productnaphthoate synthase menb (dihydroxynaphthoic acid synthetase) (dhna synthetase)
CommentsMb0562c, menB, len: 314 aa. Equivalent to Rv0548c,len: 314 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 314 aa overlap). Probable menB,naphthoate synthase (dihydroxynaphthonic acid synthase) (EC 4.1.3.36), equivalent to NP_302473.1|NC_002677 naphthoate synthase from Mycobacterium leprae (300 aa). Also similar to others e.g. MENB_ECOLI|P27290 naphthoate synthase from Escherichia coli (285 aa), FASTA scores: opt: 599, E(): 9.3e-33, (48.1 identity in 285 aa overlap); etc. BELONGS TO THE ENOYL-COA HYDRATASE/ISOMERASE FAMILY.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS640256641200-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0562c|menB
MVAPAGEQGRSSTALSDNPFDAKAWRLVDGFDDLTDITYHRHVDDATVRVAFNRPEVRNAFRPHTVDELYRVLDHARMSPDVGVVLLTGNGPSPKDGGWAFCSGGDQRIRGRSGYQYASGDTADTVDVARAGRLHILEVQRLIRFMPKVVICLVNGWAAGGGHSLHVVCDLTLASREYARFKQTDADVGSFDGGYGSAYLARQVGQKFAREIFFLGRTYTAEQMHQMGAVNAVAEHAELETVGLQWAAEINAKSPQAQRMLKFAFNLLDDGLVGQQLFAGEATRLAYMTDEAVEGRDAFLQKRPPDWSPFPRYF
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