Gene Mb0568 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namemenC
Gene length981 bp
IdentifierMb0568
Location 645733 bp
Protein summary information
Molecular mass33975.2 Da
Isoelectric point4.5965
Protein length326 amino acids
Orthologues
M. tuberculosisRv0553
Cross-references
UniProtP65426
UniProtKB/TrEMBLX2BFD4, P65426
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE MUCONATE CYCLOISOMERASE MENC (CIS,CIS-MUCONATE LACTONIZING ENZYME) (MLE)
CommentsMb0568, menC, len: 326 aa. Equivalent to Rv0553,len: 326 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 326 aa overlap). Probable menC,muconate cycloisomerase (EC 5.5.1.1), equivalent to NP_302476.1|NC_002677 putative isomerase/racemase from Mycobacterium leprae (334 aa). Also similar to other muconate cycloisomerases e.g. TCBD_PSESP|P27099 chloromuconate cycloisomerase (370 aa), FASTA scores: opt: 249, E(): 7.8e-09, (32.7% identity in 199 aa overlap). Also similar to O-succinylbenzoate-CoA synthases. BELONGS TO THE MANDELATE RACEMASE / MUCONATE LACTONIZING ENZYME FAMILY.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS645733646713+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0568|menC
MIPVLPPLEALLDRLYVVALPMRVRFRGITTREVALIEGPAGWGEFGAFVEYQSAQACAWLASAIETAYCAPPPVRRDRVPINATVPAVAAAQVGEVLARFPGARTAKVKVAEPGQSLADDIERVNAVRELVPMVRVDANGGWGVAEAVAAAAALTADGPLEYLEQPCATVAELAELRRRVDVPIAADESIRKAEDPLAVVRAQAADIAVLKVAPLGGISALLDIAARIAVPVVVSSALDSAVGIAAGLTAAAALPELDHACGLGTGGLFEEDVAEPAAPVDGFLAVARTTPDPARLQALGAPPQRRQWWIDRVKACYSLLVPSFG
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