Gene Mb0583 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namecyp135B1
Gene length1419 bp
IdentifierMb0583
Location 660693 bp
Protein summary information
Molecular mass50687.5 Da
Isoelectric point10.3671
Protein length472 amino acids
Orthologs
M. tuberculosis H37RvRv0568
M. tuberculosis MTBC0mtbc0_000598
Cross-references
UniProtP63716
UniProtKB/TrEMBLX2BFF0, P63716
General annotation
TypeCDS
FunctionUnknown
ProductPOSSIBLE CYTOCHROME P450 135B1 CYP135B1
CommentsMb0583, cyp135B1, len: 472 aa. Equivalent to Rv0568, len: 472 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 472 aa overlap). Possible cyp135B1, cytochrome P450 (EC 1.14.-.-), similar to putative cytochrome P-450 monoxygenases and other cytochrome P-450 related enzymes e.g. P29980|CPXN_ANASP PROBABLE CYTOCHROME P450 from Anabaena sp. strain PCC 7120 (459 aa), FASTA scores: opt: 525, E(): 7.2e-27, (31.9% identity in 417 aa overlap); etc. Also similar to others from Mycobacterium tuberculosis e.g. Rv0327c|NP_214841.1|NC_000962|CYP135A1|MT0342|MTCY63.32c PUTATIVE CYTOCHROME P450 (449 aa), FASTA scores: opt: 1080, E(): 0, (40.5% identity in 444 aa overlap); Rv3685c|NP_218202.1|NC_000962 PUTATIVE CYTOCHROME P450 (476 aa); Rv0136|NP_214650.1|NC_000962 PUTATIVE CYTOCHROME P450 (441 aa); etc. Contains cytochrome P450 cysteine heme-iron ligand signature (PS00086).
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS660693662111+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0583|cyp135B1
MSGTSSMGLPPGPRLSGSVQAVLMLRHGLRFLTACQRRYGSVFTLHVAGFGHMVYLSDPAAIKTVFAGNPSVFHAGEANSMLAGLLGDSSLLLIDDDVHRDRRRLMSPPFHRDAVARQAGPIAEIAAANIAGWPMAKAFAVAPKMSEITLEVILRTVIGASDPVRLAALRKVMPRLLNVGPWATLALANPSLLNNRLWSRLRRRIEEADALLYAEIADRRADPDLAARTDTLAMLVRAADEDGRTMTERELRDQLITLLVAGHDTTATGLSWALERLTRHPVTLAKAVQAADASAAGDPAGDEYLDAVAKETLRIRPVVYDVGRVLTEAVEVAGYRLPAGVMVVPAIGLVHASAQLYPDPERFDPDRMVGATLSPTTWLPFGGGNRRCLGATFAMVEMRVVLREILRRVELSTTTTSGERPKLKHVIMVPHRGARIRVRATRDVSATSQATAQGAGCPAARGGGPSRAVGSQ
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