Gene Mb0618c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nametcrA
Gene length762 bp
IdentifierMb0618c
Location 700283 bp
Protein summary information
Molecular mass28184.3 Da
Isoelectric point8.8261
Protein length253 amino acids
Orthologs
M. tuberculosis H37RvRv0602c
M. tuberculosis MTBC0mtbc0_000632
Cross-references
UniProtA0A1R3XVY5
InterProIPR001789, IPR001867, IPR011006, IPR011991
UniProtKB/TrEMBLQ7U1N4
General annotation
TypeCDS
FunctionUnknown
Producttwo component dna binding transcriptional regulatory protein tcra
CommentsMb0618c, tcrA, len: 253 aa. Equivalent to Rv0602c,len: 253 aa, from Mycobacterium tuberculosis strain H37Rv,(99.6% identity in 253 aa overlap). Probable tcrA,two-component DNA-binding response regulator, highly similar to others e.g. NP_107959.1|NC_002678 two-component response regulator from Mesorhizobium loti (239 aa); etc. Also similar to many other Mycobacterium tuberculosis two-component regulators e.g. Q50806|MTCY10G2.16|Rv1033c RESPONSE REGULATOR HOMOLOG TRCR (TCRV) (257 aa), FASTA score: (47.4 identity in 232 aa overlap); etc.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS700283701044-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0618c|tcrA
MADETTMRAGRGPGRACGRVSGVRILVIEDEPKMTALLARALTEEGHTVDTVADGRHAVAAVDGGDYDAVVLDVMLPGIDGFEVCARLRRQRVWTPVLMLTARGAVTDRIAGLDGGADDYLTKPFNLDELFARLRALSRRGPIPRPPTLEAGDLRLDPSEHRVWRADTEIRLSHKEFTLLEALIRRPGIVHTRAQLLERCWDAAYEARSNIVDVYIRYLRDKIDRPFGVTSLETIRGAGYRLRKDGGRHALPR
Bibliography
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