Gene Mb0636 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namegalK
Gene length1092 bp
IdentifierMb0636
Location 713962 bp
Protein summary information
Molecular mass37572.4 Da
Isoelectric point6.3144
Protein length363 amino acids
Orthologues
M. tuberculosisRv0620
Cross-references
UniProtQ7U1L7
UniProtKB/TrEMBLX2BFN2, Q7U1L7
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE GALACTOKINASE GALK (GALACTOSE KINASE)
CommentsMb0636, galK, len: 363 aa. Equivalent to Rv0620,len: 363 aa, from Mycobacterium tuberculosis strain H37RV,(99.7% identity in 362 aa overlap). Probable galK,galactokinase (EC 2.7.1.6), similar to others e.g. P13227|GAL1_STRLI GALACTOKINASE from Streptomyces lividans (397 aa); P06976|GAL1_ECOLI galactokinase from Escherichia coli (381 aa), FASTA scores: opt: 669, E(): 0, (35.9% identity in 365 aa overlap); etc. Contains PS00106 Galactokinase signature and PS00560 Serine carboxypeptidases, histidine active site. BELONGS TO THE GHMP KINASE FAMILY. GALK SUBFAMILY.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS713962715053+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0636|galK
MTVSYGAPGRVNLIGEHTDYNLGFALPIALPRRTVVTFTPEHTGAITARSDRADGSARIPLDTTPGQVTGWAAYAAGAIWALRGAGHPVPGGAMSITSDVEIGSGLSSSAALIGAVLGAVGAATGTRIDRLERARLAQRAENDYVGAPTGLLDHLAALFGAPKTALLIDFRDITVRPVAFDPDACDVVLLLMDSRARHRHAGGEYALRRASCERAAADLGVSSLRAVQDRGLAALGAIADPIDARRARHVLTENQRVLDFAAALADSDFTAAGQLLTASHESMREDFAITTERIDLIAESAVRAGALGARMTGGGFGGAVIALVPADRARDVADTVRRAAVTAGYDEPAVSRTYAAPGAAECC
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