Gene Mb0649c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameechA3
Gene length696 bp
IdentifierMb0649c
Location 729828 bp
Protein summary information
Molecular mass24354.9 Da
Isoelectric point5.6229
Protein length231 amino acids
Orthologs
M. tuberculosis H37RvRv0632c
M. tuberculosis MTBC0mtbc0_000665
Cross-references
UniProtA0A1R3XW12
InterProIPR001753
UniProtKB/TrEMBLQ7U1K8
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE ENOYL-COA HYDRATASE ECHA3 (ENOYL HYDRASE) (UNSATURATED ACYL-COA HYDRATASE) (CROTONASE)
CommentsMb0649c, echA3, len: 231 aa. Equivalent to Rv0632c,len: 231 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 231 aa overlap). Probable echA3,enoyl-CoA hydratase (EC 4.2.1.17), almost identical to the MTU88877_1 enoyl-coA hydratase of Mycobacterium tuberculosis field isolate NTI64719, FASTA score: (92.4% identity in 184 aa overlap). Also similar to others e.g. P24162|ECHH_RHOCA enoyl-CoA hydratase from Rhodobacter capsulatus (Rhodopseudomonas capsulata) (257 aa), FASTA scores: opt: 206, E(): 6.3e-07, (31.5% identity in 232 aa overlap); etc.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS729828730523-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0649c|echA3
MSDPVSYTRKDSIAVISMDDGKVNALGPAMQQALNAAIDNADRDDVGALVITGNGRVFSGGFDLKILTSGEVQPAIDMLRGGFELAYRLLSYPKPVVMACTGHAIAMGAFLLSCGDHRVAAHAYNIQANEVAIGMTIPYAALEIMKLRLTRSAYQQATGLAKTFFGETALAAGFIDEIALPEVVVSRAEEAAREFAGLNQHAHAATKLRSRADALTAIRAGIDGIAAEFGL
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