Gene Mb0663c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namemmaA2
Gene length864 bp
IdentifierMb0663c
Location 739533 bp
Protein summary information
Molecular mass32681.3 Da
Isoelectric point5.5269
Protein length287 amino acids
Orthologs
M. tuberculosis H37RvRv0644c
M. tuberculosis MTBC0mtbc0_000682
Cross-references
UniProtQ7U1J9
UniProtKB/TrEMBLX2BFN6, Q7U1J9
General annotation
TypeCDS
FunctionUnknown
ProductMETHOXY MYCOLIC ACID SYNTHASE 2 MMAA2 (METHYL MYCOLIC ACID SYNTHASE 2) (MMA2) (HYDROXY MYCOLIC ACID SYNTHASE)
CommentsMb0663c, mmaA2, len: 287 aa. Equivalent to Rv0644c,len: 287 aa, from Mycobacterium tuberculosis strain H37Rv,(99.7% identity in 287 aa overlap). mmaA2, methoxy mycolic acid synthase 2 (methyltransferase) (EC 2.1.1.-) (see citations below). Equivalent to AAC44874|AAC44874.1|cmaC methyl transferase (mycolic acid modification protein) from Mycobacterium bovis BCG strain Pasteur (287 aa); and highly similar to others from Mycobacteria e.g. upstream ORF P72028|mmaA4|Rv0642c|MTCY20H10.23c PUTATIVE METHOXY MYCOLIC ACID SYNTHASE 4 from Mycobacterium tuberculosis (301 aa). Note that alternative start is at position 739247.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS739533740396-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0663c|mmaA2
MVNDLTPHFEDVQAHYDLSDDFFRLFLDPTQTYSCAHFEREDMTLEEAQIAKIDLALGKLGLQPGMTLLDIGCGWGATMRRAIAQYDVNVVGLTLSKNQAAHVQKSFDEMDTPLDRRVLLAGWEQFNEPVDRIVSIGAFEHFGHDRHADFFARAHKILPPDGVLLLHTITGLTRQQMVDHGLPLTLWLARFLKFIATEIFPGGQPPTIEMVEEQSAKTGFTLTRRQSLQPHYARTLDLWAEALQEHKSEAIAIQSEEVYERYMKYLTGCAKLFRVGYIDVNQFTLAK
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