Gene Mb0694 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameechA5
Gene length792 bp
IdentifierMb0694
Location 776552 bp
Protein summary information
Molecular mass27441.4 Da
Isoelectric point7.89
Protein length263 amino acids
Orthologs
M. tuberculosis H37RvRv0675
M. tuberculosis MTBC0mtbc0_000714
Cross-references
UniProtA0A1R3XY72
InterProIPR001753, IPR018376
UniProtKB/TrEMBLQ7U1H5
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE ENOYL-COA HYDRATASE ECHA5 (ENOYL HYDRASE) (UNSATURATED ACYL-COA HYDRATASE) (CROTONASE)
CommentsMb0694, echA5, len: 263 aa. Equivalent to Rv0675,len: 263 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 263 aa overlap). Probable echA5,enoyl-CoA hydratase (EC 4.2.1.17), similar to several e.g. NP_252116.1|NC_002516 probable enoyl CoA-hydratase/isomerase from Pseudomonas aeruginosa (256 aa); Q20376 PROTEIN SIMILAR TO ENOYL-COA HYDRATASE from Caenorhabditis elegans (258 aa), FASTA scores: opt: 697,E(): 0, (47.3% identity in 245 aa overlap); etc. Also similar to others from Mycobacterium tuberculosis e.g. Z92669|MTCY8D5_17 (262 aa), FASTA scores: opt: 493, E(): 3.6e-25, (39.1% identity in 243 aa overlap); etc.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS776552777343+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0694|echA5
MSDLVRVERKGRVTTVILNRPASRNAVNGPTAAALCAAFEQFDRDDAASVAVLWGAGGTFCAGADLKAFGTPEANSVHRTGPGPMGPSRMMLSKPVIAAVSGYAVAGGLELALWCDLRVAEEDAVFGVFCRRWGVPLIDGGTVRLPRLIGHSRAMDMILTGRGVPADEALAMGLANRVVPKGQARQAAEELAAQLAALPQQCLRSDRLSALHQWGLPESAALDLEFASIARVAGEALEGARRFAAGAGRHGAPAPRAEQGDTL
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