Gene Mb0767 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namePE_PGRS9
Gene length2394 bp
IdentifierMb0767
Location 837525 bp
Protein summary information
Molecular mass65447.3 Da
Isoelectric point3.7577
Protein length797 amino acids
Orthologues
M. tuberculosisRv0746
Cross-references
UniProtA0A1R3XW92
InterProIPR000084
UniProtKB/TrEMBLQ7U1D4
General annotation
TypeCDS
FunctionUnknown
Productpe-pgrs family protein pe_pgrs9
CommentsMb0767, PE_PGRS9, len: 797 aa. Equivalent to Rv0746, len: 783 aa, from Mycobacterium tuberculosis strain H37Rv, (89.7% identity in 829 aa overlap). Member of the Mycobacterium tuberculosis PE family, PGRS subfamily of gly-rich proteins, highly similar to part of MTCY28.25c|Rv1759c|Z95890 antigen wag22 from M. tuberculosis (914 aa), FASTA scores: opt: 2429, E(): 0,(56.9% identity in 873 aa overlap). Also similar to other PE-PGRS FAMILY PROTEINS e.g. AL0212|MTV008_46 FASTA score: (48.8% identity in 887 aa overlap); etc. REMARK-M.bovis-M.tuberculosis: In Mycobacterium bovis, two 48 bp deletions, and a 138 bp insertion leads to a longer product compared to its homolog in Mycobacterium tuberculosis strain H37Rv (797 aa versus 783 aa).
Functional categoryPe/ppe
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS837525839918+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0767|PE_PGRS9
MSFVLAMPEVLGSAATDLAALGSVLGAADAAAAATTTGIVAAVQDEVSAAIAALFSAHGRAYQVASAQAAAVHAQFVEALSAGAGAYASAEAAGAAVLANPAQSVQQDLLAAVNAQSVALTGRPLIGNGANGAPGTGANGAPGGWLLGNGGAGGSAAAGSGLPGGAGGAAGLFGTGGAGGAGGSSTVGDGGAGGAGGSGGWLLGTGGVGGVGGLGAGAGGAGGVGGAGGLLGAGGHGGAGGLGAVTGGVGGAGGAGGLLAGLLAGPGGAGGTGGRGFLNDGGVGGAGGNAGLLFGAGGTGGSGGAGLGGDGGAGGAGGNAGVLFGNAGSGGTGGFGDTDGGAGGAGGDAGWLGSGGVGGAGGFGETGDGGVGGAGGKAGLLIGNGGAGGAGVLIGNGGNAGIGGTGPTAGDTGAGGISGLLLGADGFNAPASASPLHTLKQQALAAINAPTQTLTGRPLIGNGTPGAVGSGATGAPGGWLLGDGGAGGSGAAGSGAPGGAGGAAGLWGTGGAGGAGGWLLGDGGAGGIGGASTVLGGTGGGGGVGGLWGAGGAGGAGGTGLVGGDGGAGGAGGTGGLLAGLIGAGGGHGGTGGLNTNGDGGVGGAGGNAGMLAGPGGAGGAGGDGENLDTGGDGGAGGSAGLLFGSGGAGGAGGFGFLGGDGGAGGNAGLLLSSGGAGGFGGFGTAGGVGGAGGNAGWLGFGGAGGIGGIGGNANGGAGGNGGTGGQLWGSGGAGGEGGAALSVGDTGGAGGVGGSAGLIGTGGNGGNGGTGANAGSPGTGGAGGLLLGQNGLNGLP
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