Gene Mb0768 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namePE_PGRS10
Gene length2730 bp
IdentifierMb0768
Location 840317 bp
Protein summary information
Molecular mass73483.3 Da
Isoelectric point4.0107
Protein length909 amino acids
Orthologs
M. tuberculosis H37RvRv0747
Cross-references
UniProtA0A1R3XWC7
InterProIPR000084
UniProtKB/TrEMBLQ7U1D3
General annotation
TypeCDS
FunctionUnknown
Productpe-pgrs family protein pe_pgrs10
CommentsMb0768, PE_PGRS10, len: 909 aa. Equivalent to Rv0747, len: 801 aa, from Mycobacterium tuberculosis strain H37Rv, (86.6% identity in 912 aa overlap). Member of the Mycobacterium tuberculosis PE family, PGRS subfamily of gly-rich proteins, highly similar to part of MTCY28.25c|Rv1759c|Z95890 antigen wag22 from M. tuberculosis (914 aa), FASTA scores: opt: 2772, E(): 0,(60.9% identity in 941 aa overlap). Also similar to other PE-PGRS FAMILY PROTEINS e.g. Z95844|MTCY493_2 FASTA score: (50.2% identity in 815 aa overlap). Contains PS00012 Phosphopantetheine attachment site. REMARK-M.bovis-M.tuberculosis: In Mycobacterium bovis,insertions of 168 bp and 105 bp, a 11 bp for 71 bp substitution, and a 9 bp deletion (cggcaacgg-*), leads to a longer product compared to the homolog in Mycobacterium tuberculosis strain H37Rv (909 aa versus 801 aa).
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS840317843046+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb0768|PE_PGRS10
MSWVMVSPELVVAAAADLAGIGSAISSANAAAAVNTTGLLTAGADEVSTAIAALFGAQGQAYQAASAQAAAFYAQFVQALSAGGGAYAAAEAAAVSPLLAPINAQFVAATGRPLIGNGANGAPGTGANGGPGGWLIGNGGAGGSGAPGAGAGGNGGAGGLFGSGGAGGAGGNAFGAGEVGGAGGAGGNAMLFGAGGAGGAGGAGGNAGMLFGAAGVGGVGGFSNGGATGGAGGAGGAGGLFTTGGVGGAGGAGGDGGDGGAGGLFGAGGTGGAGGFGTAVLAGTGGAGGPGGAGGLFGAGGEGGSGGSGNLTGGAGGAGGNAGTLATGDGGAGGTGGASRSGGFGGAGGAGGDAGMFFGSGGSGGAGGAGGSGGFGLPSGGKGGAGGDAGMLFGSGGSGGAGGISRSVGDGAAGGAGGAPGLIGNGGNGGNGGASTGGGDGGPGGAGGTGVLIGNGGSGGTGATLGKAGIGGTGGVLLGLDGFTAPASTSPLHTLQQDVINMVNDPFQTLTGRPLIGNGANGTPGTGADGGAGGWLFGNGGNGGQGTIGGVNGGAGGAGGAGGILFGTGGTGGSGGPGATGLGGIGGAGGAALLFGSGGAGGSGGAGAVGGNGGAGGNAGALLGAAGAGGAGGAGAVGGNGGAGGNGGLFANGGAGGPGGFGSPAGAGGIGGAGGNGGLFGAGGTGGAGGGSTLAGGAGGAGGNGGLFGAGGTGGAGSHSTAAGVSGGAGGAGGDAGLLSLGASGGAGGSGGSSLTAAGVVGGIGGAGGLLFGSGGAGGSGGFSNSGNGGAGGAGGDAGLLVGSGGAGGAGASATGAATGGDGGAGGKSGAFGLGGDGGAGGATGLSGAFHIGGKGGVGGSAVLIGNGGNGGNGGNSGNAGKSGGAPGPSGAGGAGGLLLGENGLNGLM
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